Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS,
respectively, are produced during normal cell function and in response to various stimuli. An …

Abstract Thioredoxins (Trxs), glutaredoxins (Grxs), and peroxiredoxins (Prxs) have been
characterized as electron donors, guards of the intracellular redox state, and “antioxidants” …

Over the last decade fundamentally new features have been revealed for the participation of
glutathione and glutathione-dependent enzymes (glutathione transferase and glutaredoxin) …

Biological information is stored by DNA and manifested by proteins. RNA serves as the
conduit: 1 The flow of information through RNA is essential for known life. By catalyzing the …

Glutaredoxins utilize the reducing power of glutathione to maintain and regulate the cellular
redox state and redox-dependent signaling pathways, for instance, by catalyzing reversible …

Bacteria are simple and cost effective hosts for producing recombinant proteins. However,
their physiological features may limit their use for obtaining in native form proteins of some …

Reactive oxygen species (ROS) and the cellular thiol redox state are crucial mediators of
multiple cell processes like growth, differentiation, and apoptosis. Excessive ROS production …

The redox poise of the mitochondrial glutathione pool is central in the response of
mitochondria to oxidative damage and redox signaling, but the mechanisms are uncertain …

The molecular mechanism of action of macrophage migration inhibitory factor (MIF), a
cytokine with a critical role in the immune and inflammatory response, has not yet been …

Glutaredoxin (Grx) is a glutathione-dependent hydrogen donor for ribonucleotide reductase.
Today glutaredoxins are known as a multifunctional family of GSH-disulfide-oxidoreductases …