Abstract PI3K/AKT/mTOR pathway is one of the most important signaling pathways involved
in normal cellular processes. Its aberrant activation modulates autophagy, epithelial …

Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune
system to eliminate tumors. Immune checkpoint inhibitors (ICIs) block negative regulatory …

Background Genetic alterations and epigenetic modifications are two main factors involved
in gastric carcinogenesis, progression, and metastasis. Several miRNAs such as miRNA-9 …

Purpose We aimed to determine optimal cut-off points of plasma levels of ghrelin and serum
levels of pepsinogen I, II, and their ratio for screening of gastric cancer (GC). Methods Blood …

Gastric cancer is among the commonplace causes of cancer death worldwide. Sonic
hedgehog (Shh) signaling is an important pathway which may be dysregulated in many …

Cancer stem cells (CSCs) show a remarkable sub class of cancer cells population which
have a potential to organize and regulate stemness properties which possess a main …

One of the most important issues in cancer progression is caner stem cells (CSCs) which
have illustrated that the bulk tumors can arise from a special combination of cells …

Gastric cancer (GC) or human gastric adenocarcinoma is one of the most commonplace type
of serious cancers and also the most common cause of cancer-related mortality in the world …

Colorectal cancer (CRC) is distinguished by epigenetic elements like DNA methylation,
histone modification, histone acetylation and RNA remodeling which is related with genomic …

Recurrent pregnancy Loss (RPL) is a frequent and upsetting condition. Besides the
prevalent cause of RPL including chromosomal defects in the embryo, the effect of …