The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities

Z Zhang, Y Sun, Y Li, X Song, R Wang… - European Journal of …, 2024 - Elsevier
Marine-derived piperazine alkaloids (MDPAs) constitute a significant group of natural
compounds known for their diverse structures and biological activities. Over the past five …

Effect of cell adhesiveness of Cell Dome shell on enclosed HeLa cells

R Kazama, S Sakai - Journal of bioscience and bioengineering, 2024 - Elsevier
The Cell Dome is a dome-shaped structure (diameter: 1 mm, height: 270 μm) with cells
enclosed within a cavity, covered by a hemispherical hydrogel shell, and immobilized on a …

Cell Dome-based transfection array for non-adherent suspension cells

R Kazama, S Fujita, S Sakai - Biochemical Engineering Journal, 2025 - Elsevier
Cell-based microarrays are valuable tools for analyzing cellular functions. However, a
significant limitation of conventional microarrays is their inapplicability to non-adherent cells …

[HTML][HTML] Development of Hemispherical 3D Models of Human Brain and B Cell Lymphomas Using On-Chip Cell Dome System

R Kazama, R Ishikawa, S Sakai - Bioengineering, 2024 - mdpi.com
Lymphocytes are generally non-adherent. This makes it challenging to fabricate three-
dimensional (3D) structures mimicking the three-dimensional lymphoma microenvironment …