Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Nanoarchitectured structure and surface biofunctionality of mesoporous silica nanoparticles

RK Kankala, YH Han, J Na, CH Lee, Z Sun… - Advanced …, 2020 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs), one of the important porous materials, have
garnered interest owing to their highly attractive physicochemical features and …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors

FU Din, W Aman, I Ullah, OS Qureshi… - International journal …, 2017 - Taylor & Francis
Nanotechnology has recently gained increased attention for its capability to effectively
diagnose and treat various tumors. Nanocarriers have been used to circumvent the …

A multifunctional nanoplatform against multidrug resistant cancer: merging the best of targeted chemo/gene/photothermal therapy

W Cheng, J Nie, N Gao, G Liu, W Tao… - Advanced Functional …, 2017 - Wiley Online Library
Synergistic therapy that combines chemo‐, gene‐, or photothermal means shows great
potential for enhancing the therapeutic effects on cancers. Tumor‐targeted nanoparticles …

Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: An update

RR Castillo, D Lozano, B González… - Expert opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction Mesoporous silica nanoparticles (MSNs) are outstanding
nanoplatforms for drug delivery. Herein, the most recent advances to turn MSN-based …

Functionalized mesoporous silica nanoparticles and biomedical applications

TTH Thi, TNQ Nguyen, DT Hoang, DH Nguyen - Materials Science and …, 2019 - Elsevier
Since the first report in early 1990s, mesoporous silica nanoparticles (MSNs) have
progressively attracted the attention of scientists due to their potential applications in physic …

siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells

R Heidari, P Khosravian, SA Mirzaei, F Elahian - Scientific reports, 2021 - nature.com
Although siRNA is a promising technology for cancer gene therapy, effective cytoplasmic
delivery has remained a significant challenge. In this paper, a potent siRNA transfer system …

Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy

J Zhang, H Tang, Z Liu, B Chen - International journal of …, 2017 - Taylor & Francis
Chemotherapy is still one of the main cancer therapy treatments, but the curative effect of
chemotherapy is relatively low, as such the development of a new cancer treatment is highly …

[HTML][HTML] Mesoporous silica nanoparticles as carriers for therapeutic biomolecules

RR Castillo, D Lozano, M Vallet-Regí - Pharmaceutics, 2020 - mdpi.com
The enormous versatility of mesoporous silica nanoparticles permits the creation of a large
number of nanotherapeutic systems for the treatment of cancer and many other pathologies …