Challenges in Monte Carlo simulations as clinical and research tool in particle therapy: a review

S Muraro, G Battistoni, AC Kraan - Frontiers in Physics, 2020 - frontiersin.org
The use and interest in Monte Carlo (MC) techniques in the field of medical physics have
been rapidly increasing in the past years. This is the case especially in particle therapy …

[HTML][HTML] A survey of practice patterns for adaptive particle therapy for interfractional changes

P Trnkova, Y Zhang, T Toshito, B Heijmen… - Physics and imaging in …, 2023 - Elsevier
Background and purpose Anatomical changes may compromise the planned target
coverage and organs-at-risk dose in particle therapy. This study reports on the practice …

GPU‐accelerated Monte Carlo‐based online adaptive proton therapy: a feasibility study

H Feng, SH Patel, WW Wong, JE Younkin… - Medical …, 2022 - Wiley Online Library
Purpose To develop an online graphic processing unit (GPU)‐accelerated Monte Carlo‐
based adaptive radiation therapy (ART) workflow for pencil beam scanning (PBS) proton …

Evaluation of the clinical value of automatic online dose restoration for adaptive proton therapy of head and neck cancer

E Borderías-Villarroel, V Taasti, W Van Elmpt… - Radiotherapy and …, 2022 - Elsevier
Introduction Intensity modulated proton therapy (IMPT) is highly sensitive to anatomical
variations which can cause inadequate target coverage during treatment. This study …

Commissioning of GPU–Accelerated Monte Carlo Code FRED for Clinical Applications in Proton Therapy

J Gajewski, M Garbacz, CW Chang, K Czerska… - Frontiers in …, 2021 - frontiersin.org
We present commissioning and validation of Fred, a graphical processing unit (GPU)–
accelerated Monte Carlo code, for two proton beam therapy facilities of different beam line …

Automated Monte-Carlo re-calculation of proton therapy plans using Geant4/Gate: implementation and comparison to plan-specific quality assurance measurements

AH Aitkenhead, P Sitch, JC Richardson… - The British Journal of …, 2020 - academic.oup.com
Objectives: Software re-calculation of proton pencil beam scanning plans provides a method
of verifying treatment planning system (TPS) dose calculations prior to patient treatment …

Dose mimicking based strategies for online adaptive proton therapy of head and neck cancer

E Borderias-Villarroel, A Fredriksson… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. To compare a not adapted (NA) robust planning strategy with three fully
automated online adaptive proton therapy (OAPT) workflows based on the same …

[HTML][HTML] Inter-and intrafractional 4D dose accumulation for evaluating ΔNTCP robustness in lung cancer

A Smolders, AC Hengeveld, S Both, R Wijsman… - Radiotherapy and …, 2023 - Elsevier
Background and purpose Model-based selection of proton therapy patients relies on a
predefined reduction in normal tissue complication probability (NTCP) with respect to photon …

Future technological developments in proton therapy–A predicted technological breakthrough

M Vidal, C Moignier, A Patriarca, M Sotiropoulos… - Cancer …, 2021 - Elsevier
In the current spectrum of cancer treatments, despite high costs, a lack of robust evidence
based on clinical outcomes or technical and radiobiological uncertainties, particle therapy …

The GATE-RTion/IDEAL independent dose calculation system for light ion beam therapy

L Grevillot, DJ Boersma, H Fuchs, M Bolsa-Ferruz… - Frontiers in …, 2021 - frontiersin.org
Patient specific quality assurance can be improved using an independent dose calculation
system. In addition, the implementation of such a system may support light ion beam therapy …