Purpose Poly (lactic-co-glycolic acid) has received much academic attention for developing
nanotherapeutics and FDA has approved it for several applications. An important parameter …

Oral sildenafil (SDF) is used to treat pulmonary arterial hypertension (PAH), and its
bioavailability is approximately 40%. Several formulations of nano and microparticles (for …

The aim of the present study was to optimize lorazepam loaded PLGA nanoparticles (Lzp‐
PLGA‐NPs) by investigating the effect of process variables on the response using Box …

Background Every cell in the human body is vital because it maintains equilibrium and
carries out a variety of tasks, including growth and development. These activities are carried …

The aim of this work was to use the quality-by-design (QbD) approach in the development of
long-circulating liposomes co-loaded with curcumin (CUR) and doxorubicin (DOX) and to …

The aim of this work was to study the effect of different processing and formulation
parameters on the preparation of sildenafil (SD) transfersomes utilizing the Plackett–Burman …

Spironolactone (SL) is a US Food and Drug Administration-approved drug for the treatment
of hypertension and various edematous conditions. SL has gained a lot of attention for …

Impaired healing of diabetic ulcers is one of the major complications of diabetic patients due
to high susceptibility to microbial infections, impaired lymphianogenesis, edema, and …

Age-related macular degeneration (AMD) is the leading cause of certified vision loss
worldwide. The standard treatment for neovascular AMD involves repeated intravitreal …

The dual drug loaded poly (dl-lactic-co-glycolic acid)(PLGA 1) nanoparticles (TOP–TAM NPs
2) concurrently delivering topotecan hydrochloride (TOP 3) and tamoxifen citrate (TAM 4) …