The neurobiology of love and pair bonding from human and animal perspectives

SA Blumenthal, LJ Young - Biology, 2023 - mdpi.com
Simple Summary Being in love is a powerful emotional experience that is uniquely human;
however, animal models of pair bonding provide insights into the neurobiological processes …

Behavioral, neural, and molecular mechanisms of conditioned mate preference: the role of opioids and first experiences of sexual reward

GR Quintana, CE Mac Cionnaith, JG Pfaus - International journal of …, 2022 - mdpi.com
Although mechanisms of mate preference are thought to be relatively hard-wired,
experience with appetitive and consummatory sexual reward has been shown to condition …

Distinct BOLD activation profiles following central and peripheral oxytocin administration in awake rats

CF Ferris, JR Yee, WM Kenkel, KM Dumais… - Frontiers in behavioral …, 2015 - frontiersin.org
A growing body of literature has suggested that intranasal oxytocin (OT) or other systemic
routes of administration can alter prosocial behavior, presumably by directly activating OT …

The role of orgasm in the development and shaping of partner preferences

GA Coria-Avila, D Herrera-Covarrubias… - Socioaffective …, 2016 - Taylor & Francis
Background The effect of orgasm on the development and shaping of partner preferences
may involve a catalysis of the neurochemical mechanisms of bonding. Therefore …

Future targets for female sexual dysfunction

M Farmer, H Yoon, I Goldstein - The journal of sexual medicine, 2016 - academic.oup.com
Introduction Female sexual function reflects a dynamic interplay of central and peripheral
nervous, vascular, and endocrine systems. The primary challenge in the development of …

Sex differences in neural activation following different routes of oxytocin administration in awake adult rats

KM Dumais, PP Kulkarni, CF Ferris… - …, 2017 - Elsevier
The neuropeptide oxytocin (OT) regulates social behavior in sex-specific ways across
species. OT has promising effects on alleviating social deficits in sex-biased …

Activation patterns of vasopressinergic and oxytocinergic brain regions following social play exposure in juvenile male and female rats

CJ Reppucci, CK Gergely… - Journal of …, 2018 - Wiley Online Library
Social play is a highly rewarding and motivated behaviour predominately displayed by
juveniles and expressed by nearly all mammalian species. Prior work suggested that the …

Introducing compassion focused psychosexual therapy

J Vosper, C Irons, K Mackenzie-White… - Sexual and …, 2023 - Taylor & Francis
Psychosexual therapy has undergone numerous developments since the introduction of
behavioural therapy for sexual difficulties by Masters and Johnson in the 1960s. We argue …

Do rats have orgasms?

JG Pfaus, T Scardochio, M Parada… - Socioaffective …, 2016 - Taylor & Francis
Background Although humans experience orgasms with a degree of statistical regularity,
they remain among the most enigmatic of sexual responses; difficult to define and even …

Sexual experience increases oxytocin, but not vasopressin, receptor densities in the medial preoptic area, ventromedial hypothalamus, and central amygdala of male …

S Ménard, H Gelez, GA Coria-Avila, JG Pfaus - Psychoneuroendocrinology, 2022 - Elsevier
Oxytocin (OT) and vasopressin (VP) are considered to be principal neurochemical
substrates of bonding in monogamous species. We have reported previously that …