LIM and SH3 protein 1 was originally identified as a structural cytoskeletal protein with
scaffolding function. However, recent data suggest additional roles in cell signaling and …

In the recent two decades, LIM and SH3 protein 1 (LASP1) has been developed from a
simple actin-binding structural protein to a tumor biomarker and subsequently to a complex …

Mesenchymal stromal cells (MSCs) are one of major components of the tumour
microenvironment. Recent studies have shown that MSC tumour residence and their close …

The hepatitis B virus (HBV) X protein (HBX), a viral macromolecule, plays a vital role in the
development of HBV-related hepatocellular carcinoma (HCC). Increased expression of …

Background. LIM and SH3 domain protein 1 (LASP1), highly expressed in a variety of
tumors, is considered as a novel tumor metastasis biomarker. However, it is unknown which …

For patients with advanced or metastatic Hepatocellular carcinoma (HCC) who are not
suitable for surgical resection, systemic therapy has been considered to be the standard …

Abstract Background miR-203a-3p was reported as a tumor suppressor and disregulated in
many malignancies including nasopharyngeal carcinoma (NPC). However, its function in …

Significant reprogramming of epigenome is widely described during pathogenesis of breast
cancer. Transformation of normal cell to hyperplastic cell and to neoplastic phenotype is …

Abstract LIM and SH3 protein 1 (LASP1) is a metastasis-related protein reported to enhance
tumour progression in colorectal cancer (CRC). However, the underlying mechanism is still …

Cancer remains one of the most challenging diseases despite significant advances of early
diagnosis and therapeutic treatments. Cancerous tumors are composed of various cell types …