The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions

BW Dunlop, A Wong - Progress in Neuro-psychopharmacology and …, 2019 - Elsevier
Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …

HPA axis regulation in posttraumatic stress disorder: A meta-analysis focusing on potential moderators

S Schumacher, H Niemeyer, S Engel, JC Cwik… - Neuroscience & …, 2019 - Elsevier
Posttraumatic stress disorder (PTSD) is often associated with alterations in the hypothalamic–
pituitary–adrenal (HPA) axis. Previous findings are inconsistent, possibly due to trauma …

[HTML][HTML] An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo …

AL Lopresti, SJ Smith, H Malvi, R Kodgule - Medicine, 2019 - journals.lww.com
Background: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to
reduce stress and enhance wellbeing. The aim of this study was to investigate its anxiolytic …

Testosterone, DHEA and DHEA-S in patients with schizophrenia: A systematic review and meta-analysis

B Misiak, D Frydecka, O Loska, AA Moustafa… - …, 2018 - Elsevier
Neuroactive steroids, including testosterone, dehydroepiandrosterone (DHEA) and its
sulfate (DHEA-S) might play an important role in the pathophysiology of schizophrenia …

Neurobiology and treatment of posttraumatic stress disorder

A Shalev, D Cho, CR Marmar - American Journal of Psychiatry, 2024 - psychiatryonline.org
The recent worldwide surge of warfare and hostilities exposes increasingly large numbers of
individuals to traumatic events, placing them at risk of developing posttraumatic stress …

[HTML][HTML] The associations of hair cortisol and DHEA with posttraumatic stress disorder symptoms in refugees

AM de Graaff, P Cuijpers, L Boschloo, M Elsawy… - Comprehensive …, 2024 - Elsevier
Background Exposure to traumatic events, ongoing adversity, and posttraumatic stress
disorder (PTSD) are associated with altered activity of the hypothalamic-pituitary-adrenal …

Reduced Dehydroepiandrosterone-sulfate levels in the mid-luteal subphase of the menstrual cycle: implications to women's health research

A Hamidovic, F Soumare, A Naveed, J Davis, J Sun… - Metabolites, 2022 - mdpi.com
The regulation of DHEA-sulfate by steroid sulfotransferase (SULT) and steryl-sulfatase (STS)
enzymes is a vital process for the downstream formation of many steroid hormones. DHEA …

[HTML][HTML] Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomised, double …

AL Lopresti, SJ Smith, S Ali, AP Metse, J Kalns… - Journal of Functional …, 2021 - Elsevier
Abstract In this 28-day, randomised, double-blind, placebo-controlled trial, 100 adults with
self-reported poor sleep received either a placebo or a standardised Bacopa monnieri …

The stress of caring—resilience and HPA-axis activity in hair samples of youth residential caregivers

D Bürgin, N Kind, M Schröder, V Clemens… - Frontiers in …, 2020 - frontiersin.org
Background: Professional caregivers in youth residential care institutions experience
frequent verbal and physical aggression as well as multiple stressors as part of their …

Cardiovascular disease risk factors in patients with posttraumatic stress disorder (PTSD): a narrative review

M Šagud, N Jakšić, B Vuksan-Ćusa, M Lončar… - Psychiatria …, 2017 - hrcak.srce.hr
Sažetak Posttraumatic stress disorder (PTSD) is a chronic condition related to severe stress
and trauma. There is a mounting evidence about increased prevalence and mortality from …