Due to the heterogeneity of colon cancer, surgery, chemotherapy, and radiation are
ineffective in all cases. The genomic profile and biomarkers associated with the process are …

Simple Summary Wnt signaling is one of the main evolutionarily conserved developmental
pathways needed to instruct embryo formation and maintenance of organ tissues. Decades …

Biomaterial characteristics like surface roughness and wettability can determine the
phenotype of macrophages following implantation. We have demonstrated that inhibiting …

Background Colorectal cancer (CRC) development is a complex, multi-stage process,
transitioning from normal to adenomatous tissue, and then to invasive carcinoma. Despite …

Background and Objectives: PNU-74654, a Wnt/β-catenin pathway inhibitor, has an
antiproliferative effect on many cancer types; however, its therapeutic role in pancreatic …

The Wnt/β-catenin signaling pathway plays a critical role in various biological processes,
including cell proliferation, differentiation, and tissue homeostasis. Aberrant activation of this …

Cancer represents an intricate and heterogeneous ailment that evolves from a multitude of
epigenetic and genetic variations that disrupt normal cellular function. The WNT/β-catenin …

Brain cancers are among the most aggressive malignancies with high mortality and
morbidity worldwide. The pathogenesis of brain cancers is a very complicated process …

Background: Colorectal cancer (CRC) is a serious health problem, and finding new
treatments is important. There is growing evidence for the antitumor activity of probiotics …

Gastrointestinal carcinomas are a group of cancers associated with the digestive system and
its accessory organs. The most prevalent cancers related to the gastrointestinal tract are …