Recent progress of bacterial FtsZ inhibitors with a focus on peptides

H Han, Z Wang, T Li, D Teng, R Mao, Y Hao… - The FEBS …, 2021 - Wiley Online Library
In recent years, the rise of antibiotic resistance has become a primary health problem. With
the emergence of bacterial resistance, the need to explore and develop novel antibacterial …

Antibacterial activity of a new monocarbonyl analog of curcumin MAC 4 is associated with divisome disruption

CR Polaquini, BC Marques, GM Ayusso, LG Morão… - Bioorganic …, 2021 - Elsevier
Curcumin (CUR) is a symmetrical dicarbonyl compound with antibacterial activity. On the
other hand, pharmacokinetic and chemical stability limitations hinder its therapeutic …

[PDF][PDF] Identification of potential therapeutic targets for Streptococcus suis infection

B Jeffreys - 2021 - core.ac.uk
Streptococcus (S.) suis is a commensal porcine pathogen that is the leading causative agent
of bacterial meningitis and sepsis in young pigs globally. Systemic infection in swine is …

Análogos monocetônicos de curcumina: planejamento, síntese e atividades antibacteriana e antifúngica

CR Polaquini - 2020 - repositorio.unesp.br
A curcumina é um dicetônico natural com efeitos antimicrobianos promissores. Contudo,
limitações farmacocinéticas e farmacodinâmicas dificultam os seus estudos clínicos. Uma …