Since the introduction of calcium imaging to monitor neuronal activity with single-cell
resolution, optical imaging methods have revolutionized neuroscience by enabling …

Neuronal action potentials or spikes provide a long-range, noise-resistant means of
communication between neurons. As point processes single spikes contain little information …

Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

The combination of two-photon microscopy recordings and powerful calcium-dependent
fluorescent sensors enables simultaneous recording of unprecedentedly large populations …

In vivo calcium imaging through microendoscopic lenses enables imaging of previously
inaccessible neuronal populations deep within the brains of freely moving animals …

Seizures are a frequent pathophysiological feature of malignant glioma. Recent studies
implicate peritumoral synaptic dysregulation as a driver of brain hyperactivity and tumor …

The computations performed by local neural populations, such as a cortical layer, are
typically inferred from anatomical connectivity and observations of neural activity. Here we …

Calcium imaging records large-scale neuronal activity with cellular resolution in vivo.
Automated, fast, and reliable active neuron segmentation is a critical step in the analysis …

Reviewing the history of the development of artificial intelligence (AI) clearly reveals that
brain science has resulted in breakthroughs in AI, such as deep learning. At present …

Calcium imaging is a popular tool among neuroscientists because of its capability to monitor
in vivo large neural populations across weeks with single neuron and single spike …