Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease affecting
motor neurons with an incidence of about 1/100,000. Most ALS cases are sporadic, but 5 …

Classic textbook neurology teaches that amyotrophic lateral sclerosis (ALS) is a
degenerative disease that selectively affects upper and lower motor neurons and is fatal 3–5 …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by
progressive muscular paralysis reflecting degeneration of motor neurones in the primary …

We have performed a systematic review to summarize current knowledge concerning factors
related to survival in ALS and to evaluate the implications of these data for clinical trials …

Objective: To estimate the current incidence and prevalence in the United States of 12
neurologic disorders. Methods: We summarize the strongest evidence available, using data …

Background Variation in the incidence rate in epidemiological studies on amyotrophic lateral
sclerosis (ALS) may be due to a small population size and under ascertainment of patients …

Objective To determine the long‐term survival in amyotrophic lateral sclerosis (ALS) and
identify predictors of prolonged survival in a population‐based cohort of newly diagnosed …

Replicable risk factors for ALS include increasing age, family history and being male. The
male: female ratio has been reported as being between 1 and 3. We tested the hypothesis …

Objective: To describe the temporal patterns of incidence and demographic characteristics
of amyotrophic lateral sclerosis (ALS) in Piemonte and Valle d'Aosta, Italy, in the 10-year …

Amyotrophic lateral sclerosis (ALS) is a highly complex and heterogeneous
neurodegenerative disease that affects motor neurons. Since life expectancy is relatively …