Biosynthesis and potential applications of silver and gold nanoparticles and their chitosan‐based nanocomposites in nanomedicine

H Katas, NZ Moden, CS Lim… - Journal of …, 2018 - Wiley Online Library
Biosynthesized or biogenic metallic nanoparticles, particularly silver and gold nanoparticles
(AgNPs and AuNPs, respectively), have been increasingly used because of their …

Immune regulation during chronic visceral leishmaniasis

RJ Faleiro, R Kumar, LM Hafner… - PLoS neglected tropical …, 2014 - journals.plos.org
Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

Revival of leishmanization and leishmanin

T Pacheco-Fernandez, G Volpedo… - Frontiers in Cellular …, 2021 - frontiersin.org
Leishmaniasis includes a spectrum of diseases ranging from debilitating cutaneous to fatal
visceral infections. This disease is caused by the parasitic protozoa of the genus Leishmania …

[HTML][HTML] An overview on Leishmania vaccines: A narrative review article

H Rezvan, M Moafi - Veterinary research forum, 2015 - ncbi.nlm.nih.gov
Leishmaniasis is one of the major health problems and categorized as a class I disease
(emerging and uncontrolled) by World Health Organization (WHO), causing highly …

Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania

POL Moreira, PM Nogueira, RL Monte-Neto - Microorganisms, 2023 - mdpi.com
Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still
lacking a safe and effective vaccine for humans. Given this scenario, the search for a new …

Cutaneous leishmaniasis: current treatment practices in the USA for returning travelers

DP Eiras, LA Kirkman, HW Murray - Current treatment options in infectious …, 2015 - Springer
Opinion statement Leishmaniasis, a protozoal infection transmitted by sandfly bite, produces
a clinical spectrum of disease ranging from asymptomatic infection to ulcerative skin and …

Vaccines against leishmaniasis: using controlled human infection models to accelerate development

V Parkash, PM Kaye, AM Layton… - Expert Review of …, 2021 - Taylor & Francis
Introduction Leishmaniasis is a neglected tropical disease that is defined by the World
Health Organization as vaccine preventable. Although several new candidate vaccines are …

Live attenuated vaccines, a favorable strategy to provide long-term immunity against protozoan diseases

JC Solana, J Moreno, S Iborra, M Soto… - Trends in …, 2022 - cell.com
The control of diseases caused by protozoan parasites is one of the United Nations'
Sustainable Development Goals. In recent years much research effort has gone into …

Immunity to visceral leishmaniasis: implications for immunotherapy

F Khadem, JE Uzonna - Future microbiology, 2014 - Taylor & Francis
Visceral leishmaniasis, caused by Leishmania donovani, L. infantum (syn. Leishmania
chagasi), is a globally widespread disease with a burden of about 400,000 new infections …

Cutaneous infection with Leishmania major mediates heterologous protection against visceral infection with Leishmania infantum

A Romano, NA Doria, J Mendez, DL Sacks… - The Journal of …, 2015 - journals.aai.org
Visceral leishmaniasis (VL) is a fatal disease of the internal organs caused by the eukaryotic
parasite Leishmania. Control of VL would best be achieved through vaccination. However …