Ezrin is one of the members of the ezrin/radixin/moesin (ERM) family of proteins. It was
originally discovered as an actin-binding protein in the microvilli structure about forty years …

Ezrin is the cytoskeletal organizer and functions in the modulation of membrane–
cytoskeleton interaction, maintenance of cell shape and structure, and regulation of cell–cell …

Cancer metastasis is the primary cause of morbidity and mortality in cancer as it remains the
most complicated, devastating, and enigmatic aspect of cancer. Several decades of …

Abstract Lysyl oxidase-like 2 (LOXL2), a copper-dependent enzyme of the lysyl oxidase
family and its nonsecreted, catalytically dead spliced isoform L2Δ13, enhance cell migration …

Astrocytes are increasingly perceived as active partners in physiological brain function and
behaviour. The structural correlations of the glia–synaptic interaction are the peripheral …

Background Ezrin and YAP are abnormally expressed in various cancers, and play pivotal
roles in cancer initiation and development. However, the mechanisms of Ezrin in pancreatic …

Simple Summary Precision oncology is emerging as a viable option to improve survival in
patients who fail to remain disease-free even after the employment of currently available …

Abstract Aims microRNA-96 (miR-96) is considered as a tumor suppressor in multiple
malignancies. Some studies have indicated that EZRIN could be regulated by the miR-96 in …

Membrane–cytoskeleton interactions (MCIs) are mediated by actin-binding proteins (ABPs).
Ezrin is a crucial ABP that links membranes to actin filaments during lamellipodia formation …

PTEN encodes a tumor suppressor with lipid and protein phosphatase activities whose
dysfunction has been implicated in melanomagenesis; less is known about how its …