Bioavailability of hesperidin and its aglycone hesperetin—compounds found in citrus fruits as a parameter conditioning the pro-health potential (neuroprotective and …

K Wdowiak, J Walkowiak, R Pietrzak, A Bazan-Woźniak… - Nutrients, 2022 - mdpi.com
Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits.
They possess a variety of pharmacological properties such as neuroprotective and …

Triglyceride-glucose index (TyG) as a novel biomarker in the era of cardiometabolic medicine

A Avagimyan, N Pogosova, F Fogacci… - International Journal of …, 2025 - Elsevier
In the period of increasing prevalence of metabolic disorders such as obesity and diabetes,
healthcare professionals are facing significant challenges. Therefore, an accurate global …

Inflammation and Oxidative Stress in Frailty and Metabolic Syndromes—Two Sides of the Same Coin

S Dzięgielewska-Gęsiak, M Muc-Wierzgoń - Metabolites, 2023 - mdpi.com
In developed countries, aging is often seen as typical, but it is made complicated by many
disorders and co-morbidities. Insulin resistance seems to be an underlying pathomechanism …

Increased oxidative stress and inflammatory markers contrasting with the activation of the cholinergic anti-inflammatory pathway in patients with metabolic syndrome

CC Martins, MD Bagatini, JLB Simões, AM Cardoso… - Clinical …, 2021 - Elsevier
Abstract Introduction Metabolic syndrome (MetS) is a disorder that is closely associated with
risk factors that increase the chance of atherosclerosis and cardiovascular diseases. We …

Effects of high-fat diet on cardiovascular protein expression in mice based on proteomics

X Pan, X Zhang, J Ban, L Yue, L Ren… - … Syndrome and Obesity, 2023 - Taylor & Francis
Purpose To investigate the effect of high-fat diet on protein expression in mouse heart and
aorta using proteomic techniques. Methods A high-fat diet was used to construct an obese …

[HTML][HTML] Crucial Interactions between Altered Plasma Trace Elements and Fatty Acids Unbalance Ratio to Management of Systemic Arterial Hypertension in Diabetic …

I Gouaref, A Otmane, M Makrelouf… - International Journal of …, 2024 - mdpi.com
The coexistence of SAH with T2DM is a common comorbidity. In this study, we investigated
the link between altered plasma antioxidant trace elements (ATE: manganese, selenium …

[HTML][HTML] Endothelin-1 influences mechanical properties and contractility of hiPSC derived cardiomyocytes resulting in diastolic dysfunction

C Redwanz, RH Pires, D Biedenweg, S Groß… - Journal of Molecular and …, 2024 - Elsevier
A better understanding of the underlying pathomechanisms of diastolic dysfunction is crucial
for the development of targeted therapeutic options with the aim to increase the patients' …

Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated autophagy

J Yang, A Tan, T Li, H Chen - IUBMB life, 2024 - Wiley Online Library
The purpose of this study was to analyze the mechanism by which irisin affects β‐cell
pyroptosis in type 2 diabetes mellitus (T2DM). The in vivo T2DM model was established by …

正常尿白蛋白水平在多种疾病预测中的研究进展

孙珍珍, 刘欢欢, 陈开宁, 楼青青 - 中国全科医学, 2022 - chinagp.net
目前, 关于正常尿白蛋白水平与相关疾病(包括糖尿病肾病, 糖尿病视网膜病变, 心血管疾病,
代谢综合征等) 之间的关系已被逐渐重视, 越来越多的研究者也对正常尿白蛋白的范围提出了 …

脉氧下降率和心率波动率与阻塞性睡眠呼吸暂停低通气综合征患者发生心律失常的关系研究

李勇, 王颖, 陈勋, 林蔚, 张凯, 丁宁 - 中国全科医学, 2022 - chinagp.net
背景心律失常是阻塞性睡眠呼吸暂停低通气综合征(OSAHS) 患者的常见并发症, 然而OSAHS
患者心律失常的发生及严重程度与其疾病本身严重程度并不完全一致. 本研究团队前期研究发现 …