Chemical protein modification through cysteine
SB Gunnoo, A Madder - ChemBioChem, 2016 - Wiley Online Library
The modification of proteins with non‐protein entities is important for a wealth of
applications, and methods for chemically modifying proteins attract considerable attention …
applications, and methods for chemically modifying proteins attract considerable attention …
Electron paramagnetic resonance as a tool for studying membrane proteins
ID Sahu, GA Lorigan - Biomolecules, 2020 - mdpi.com
Membrane proteins possess a variety of functions essential to the survival of organisms.
However, due to their inherent hydrophobic nature, it is extremely difficult to probe the …
However, due to their inherent hydrophobic nature, it is extremely difficult to probe the …
Integrating Electron Paramagnetic Resonance Spectroscopy and Computational Modeling to Measure Protein Structure and Dynamics
Electron paramagnetic resonance (EPR) has become a powerful probe of conformational
heterogeneity and dynamics of biomolecules. In this Review, we discuss different …
heterogeneity and dynamics of biomolecules. In this Review, we discuss different …
Designing surface exposed sites on Bacillus subtilis lipase A for spin-labeling and hydration studies
Spin-labeling with electron paramagnetic resonance spectroscopy (EPR) is a facile method
for interrogating macromolecular flexibility, conformational changes, accessibility, and …
for interrogating macromolecular flexibility, conformational changes, accessibility, and …
Probing structural dynamics of membrane proteins using electron paramagnetic resonance spectroscopic techniques
ID Sahu, GA Lorigan - Biophysica, 2021 - mdpi.com
Membrane proteins are essential for the survival of living organisms. They are involved in
important biological functions including transportation of ions and molecules across the cell …
important biological functions including transportation of ions and molecules across the cell …
A metabolically engineered spin-labeling approach for studying glycans on cells
Metabolic glycan engineering (MGE) coupled with nitroxide spin-labeling (SL) was utilized
to investigate the heterogeneous environment of cell surface glycans in select cancer and …
to investigate the heterogeneous environment of cell surface glycans in select cancer and …
Darunavir-resistant HIV-1 protease constructs uphold a conformational selection hypothesis for drug resistance
Multidrug resistance continues to be a barrier to the effectiveness of highly active
antiretroviral therapy in the treatment of human immunodeficiency virus 1 (HIV-1) infection …
antiretroviral therapy in the treatment of human immunodeficiency virus 1 (HIV-1) infection …
Natural Polymorphisms D60E and I62V Stabilize a Closed Conformation in HIV-1 Protease in the Absence of an Inhibitor or Substrate
TT Tran, GE Fanucci - Viruses, 2024 - mdpi.com
HIV infection remains a global health issue plagued by drug resistance and virological
failure. Natural polymorphisms (NPs) contained within several African and Brazilian …
failure. Natural polymorphisms (NPs) contained within several African and Brazilian …
降钙素原对儿童不同类型病原菌血流感染的诊断价值
王丽伟， 刘丽红， 李达 - 临床血液学杂志, 2019 - whuhzzs.com
目的: 探讨降钙素原(PCT) 对儿童不同类型病原菌血流感染的诊断价值. 方法: 收集2014-01-
2019-01 进行血培养和PCT 检测的398 例血流感染患儿的临床资料. 分析血培养及PCT …
2019-01 进行血培养和PCT 检测的398 例血流感染患儿的临床资料. 分析血培养及PCT …
The structural, dynamic, and thermodynamic basis of darunavir resistance of a heavily mutated HIV-1 protease using molecular dynamics simulation
The human immunodeficiency virus type 1 protease (HIV-1 PR) is an important enzyme in
the life cycle of the HIV virus. It cleaves inactive pre-proteins of the virus and changes them …
the life cycle of the HIV virus. It cleaves inactive pre-proteins of the virus and changes them …