Rewiring of the serotonin system in major depression
F Vahid-Ansari, PR Albert - Frontiers in psychiatry, 2021 - frontiersin.org
Serotonin is a key neurotransmitter that is implicated in a wide variety of behavioral and
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …
Annual Research Review: Anterior Modifiers in the Emergence of Neurodevelopmental Disorders (AMEND)—a systems neuroscience approach to common …
We present the Anterior Modifiers in the Emergence of Neurodevelopmental Disorders
(AMEND) framework, designed to reframe the field of prospective studies of …
(AMEND) framework, designed to reframe the field of prospective studies of …
Kidney damage causally affects the brain cortical structure: a Mendelian randomization study
X Chen, J Kong, J Pan, K Huang, W Zhou, X Diao… - …, 2021 - thelancet.com
Background Alterations in the brain cortical structures of patients with chronic kidney
disease (CKD) have been reported; however, the cause has not been determined yet …
disease (CKD) have been reported; however, the cause has not been determined yet …
Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders
Neuropsychiatric disorders are increasingly conceptualized as overlapping spectra sharing
multi-level neurobiological alterations. However, whether transdiagnostic cortical alterations …
multi-level neurobiological alterations. However, whether transdiagnostic cortical alterations …
The ENIGMA Toolbox: multiscale neural contextualization of multisite neuroimaging datasets
Through harmonized procedures and by sharing site-specific brain metrics (for example,
cortical thickness) or aggregated statistical maps, ENIGMA has set the stage for large-scale …
cortical thickness) or aggregated statistical maps, ENIGMA has set the stage for large-scale …
Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals
According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia
(SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder …
(SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder …
Psychosis biotypes: replication and validation from the B-SNIP consortium
Current clinical phenomenological diagnosis in psychiatry neither captures biologically
homologous disease entities nor allows for individualized treatment prescriptions based on …
homologous disease entities nor allows for individualized treatment prescriptions based on …
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Cortical circuits are composed predominantly of pyramidal-to-pyramidal neuron
connections, yet their assembly during embryonic development is not well understood. We …
connections, yet their assembly during embryonic development is not well understood. We …
Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia
Brain morphology differs markedly between individuals with schizophrenia, but the cellular
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …