The interior of a living cell is a crowded, heterogenuous, fluctuating environment. Hence, a major challenge in modeling intracellular transport is to analyze stochastic processes within …
Fractional Operators with Constant and Variable Order with Application to Geo-hydrology provides a physical review of fractional operators, fractional variable order operators, and …
One of the major challenges in modern biology is to understand how the molecular components of a living cell operate in a highly noisy environment. What are the specific …
A particle's motion in crowded environments often exhibits anomalous diffusion, whose nature depends on the situation at hand and is formalized within different physical models …
K Suhling, LM Hirvonen, JA Levitt, PH Chung… - Medical photonics, 2015 - Elsevier
Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the environment and interaction of fluorescent probes. It can report on photophysical events that …
J Bourne, KM Harris - Current opinion in neurobiology, 2007 - Elsevier
Dendritic spines are the primary site of excitatory input on most principal neurons. Long- lasting changes in synaptic activity are accompanied by alterations in spine shape, size and …
Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites play an active role in transforming synaptic input into neuronal output and in defining the …
Long-term potentiation (LTP) at glutamatergic synapses is considered to underlie learning and memory and is associated with the enlargement of dendritic spines. Because the …
A Rodriguez, DB Ehlenberger, DL Dickstein, PR Hof… - PloS one, 2008 - journals.plos.org
A fundamental challenge in understanding how dendritic spine morphology controls learning and memory has been quantifying three-dimensional (3D) spine shapes with …