Blood microsampling technologies: innovations and applications in 2022

MU Thangavelu, B Wouters, A Kindt… - Analytical Science …, 2023 - Wiley Online Library
With the development of highly sensitive bioanalytical techniques, the volume of samples
necessary for accurate analysis has reduced. Microsampling, the process of obtaining small …

Multi-omics microsampling for the profiling of lifestyle-associated changes in health

X Shen, R Kellogg, DJ Panyard, N Bararpour… - Nature Biomedical …, 2024 - nature.com
Current healthcare practices are reactive and use limited physiological and clinical
information, often collected months or years apart. Moreover, the discovery and profiling of …

Applications of volumetric absorptive microsampling technique: a systematic critical review

P Dodeja, S Giannoutsos, S Caritis… - Therapeutic Drug …, 2023 - journals.lww.com
Background: Microsampling is a technique that utilizes a very small volume of biological
matrix, typically less than 50 µL, for quantitatively analyzing chemicals, drugs, and biologics …

VAMS-based blood capillary sampling for mass spectrometry-based human metabolomics studies

C Volani, C Malfertheiner, G Caprioli, S Fjelstrup… - Metabolites, 2023 - mdpi.com
Volumetric absorptive microsampling (VAMS) is a recently developed sample collection
method that enables single-drop blood collection in a minimally invasive manner. Blood …

Volumetric absorptive microsampling to enhance the therapeutic drug monitoring of tacrolimus and mycophenolic acid: a systematic review and critical assessment

AD Leino, J Takyi-Williams, MP Pai - Therapeutic Drug Monitoring, 2023 - journals.lww.com
Background: Volumetric absorptive microsampling (VAMS) is an emerging technique that
may support multisample collection to enhance therapeutic drug monitoring in solid organ …

Angong niuhuang wan attenuates LPS-induced acute lung injury by inhibiting PIK3CG/p65/MMP9 signaling in mice based on proteomics

S Li, J Hou, Q Wang, M Liu, X Xu, H Yang, X Li - Heliyon, 2023 - cell.com
Acute lung injury (ALI) is a serious pulmonary complication that often arises from
pneumonia, respiratory tract infections caused by bacteria or viruses, and other factors. It is …

Streamlining Phenotype Classification and Highlighting Feature Candidates: A Screening Method for Non-Targeted Ion Mobility Spectrometry-Mass Spectrometry (IMS …

JR Chappel, KI Kirkwood-Donelson, JN Dodds… - Analytical …, 2024 - ACS Publications
Nontargeted analysis (NTA) is increasingly utilized for its ability to identify key molecular
features beyond known targets in complex samples. NTA is particularly advantageous in …

Is this the end of dried blood spots as we know it?

TG Halvorsen, L Reubsaet - Analytical Science Advances, 2023 - Wiley Online Library
In 2017 integrated sampling and sample preparation for simplified liquid chromatography‐
mass spectrometry analysis of proteins from dried blood spots were introduced. The …

Investigating the Use of Novel Blood Processing Methods to Boost the Identification of Biomarkers for Non-Small Cell Lung Cancer: A Proof of Concept

R McMahon, N Lucas, C Hill, D Pascovici… - Journal of Proteome …, 2024 - ACS Publications
Diagnosis of non-small cell lung cancer (NSCLC) currently relies on imaging; however,
these methods are not effective for detecting early stage disease. Investigating blood-based …

[HTML][HTML] Next generation VAMS®–trypsin immobilization for instant proteolysis in bottom-up protein determination

L Reubsaet, B Thiede, TG Halvorsen - Advances in Sample Preparation, 2022 - Elsevier
The purpose of this study was to develop a smart proteolysis sampler based on
commercially available VAMS® tips employing Volumetric Absorptive Microsampling. In this …