Although there have been numerous reports from around the world of mutations in the gene
of chromosome 7 known as CFTR (cystic fibrosis transmembrane conductance regulator) …

Cystic fibrosis (CF) has been generally well defined throughout the world although its
prevalence is very difficult to ascertain for a number of reasons, including the fact that the …

We analyzed 1,954 Spanish cystic fibrosis (CF) alleles in order to define the molecular
spectrum of mutations in the CFTR gene in Spanish CF patients. Commercial panels …

BACKGROUND:: Cystic Fibrosis (CF) is the most prevalent Mendelian disorder in European
populations. Despite the fact that many Latin American countries have a predominant …

We analyzed the CFTR locus in 83 Turkish cystic fibrosis patients to identify mutations,
haplotypes, and the carrier frequency in the population. We detected 36 different mutations …

The multidrug resistance protein, MRP1, is a clinically important ATP-binding cassette
transporter in which the three membrane-spanning domains (MSDs), which contain up to 17 …

Characterization of CFTR mutations in the US Hispanic population is vital to early diagnosis,
genetic counseling, patient-specific treatment, and the understanding of cystic fibrosis (CF) …

Abstract Purpose In the United States, approximately 1/3,700 babies is born with cystic
fibrosis each year. The> 1,300 documented sequence variants pose a challenge for …

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause
cystic fibrosis (CF), a common autosomal recessive disease in Caucasians. The broad …

Cystic fibrosis (CF), which is due to mutations in the cystic fibrosis transmembrane
conductance regulator gene, is a common life-shortening disease. Although CF occurs with …