Osteoporosis is a skeletal disorder characterized by low bone mass and deterioration of
bone microarchitecture resulting in bone fragility, which impairs fixation of the implants …

Systemic treatment with strontium ranelate (SR) was performed on ovariectomized (OVX)
rats with fractured tibiae. Callus quality was assessed by radiographic, histological, micro …

Increased bone turnover with excessive bone resorption and decreased bone formation is
known to impair implant fixation. Strontium ranelate is well known as an effective …

Purpose: Human mesenchymal stem cells (hMSCs) are pursued for cell-based therapies of
bone defects. Successful use of hMSCs will require them to be osteogenically differentiated …

Ovariectomized (OVX) rats with tibial fracture received vehicle, ZA, PTH, or ZA plus PTH
treatment for 4 and 8 weeks. Bone metabolism, callus formation, and the mass of …

In the modern design, most delivery systems for bone regeneration focus on a single growth
factor (GF) or a simple mixture of multiple GFs, overlooking the coordination of proliferation …

OBJECTIVE: Low-intensity pulsed ultrasound (LIPUS) demonstrated anabolic effects on
cementoblasts, odontoblasts, and periodontal ligament cells. However, LIPUS effect on …

Methods: Cultured HGFs were exposed to osteogenic medium containing a wide range of
Dex concentrations (0.01-10 µM). The osteogenic phenotype was assessed based on …

Mesoporous bioactive glass (MBG) is a good scaffold for bone regeneration. In this study,
amino functionalized MBG (N-MBG) was used as a model scaffold to examine the effect of …

The effect of osteoporosis on implant osseointegration has been widely investigated,
whereas osteoporosis may also newly occur in patient with previously osseointegrated …