A number of papers have recently emphasised the importance of verification, validation and
sensitivity testing in computational studies within the field of biomechanical engineering …

The surgeon general of the USA defines osteoporosis as “a skeletal disorder characterized
by compromised bone strength, predisposing to an increased risk of fracture.” Measuring …

The International Society for Clinical Densitometry (ISCD) has developed Official Positions
for the clinical use of dual-energy X-ray absorptiometry (DXA) and non-DXA technologies …

Finite element analysis of computed tomography (CT) scans provides noninvasive estimates
of bone strength at the spine and hip. To further validate such estimates clinically, we …

Finite element (FE) analysis has been applied for the past 40 years to simulate the
mechanical behavior of bone. Although several validation studies have been performed on …

Low areal BMD (aBMD) is associated with increased risk of hip fracture, but many hip
fractures occur in persons without low aBMD. Finite element (FE) analysis of QCT scans …

We investigated the association of trabecular bone score (TBS) with microarchitecture and
mechanical behavior of human lumbar vertebrae. We found that TBS reflects vertebral …

While dual energy X-ray absorptiometry (DXA) is considered the gold standard to evaluate
fracture risk in vivo, in the present study, the quantitative computed tomography (QCT) …

Abstract The International Society for Clinical Densitometry (ISCD) has developed new
official positions for the clinical use of quantitative computed tomography (QCT)-based finite …

The “PTH and Alendronate” or “PaTH” study compared the effects of PTH (1‐84) and/or
alendronate (ALN) in 238 postmenopausal, osteoporotic women. We performed finite …