Animal venoms are complex mixtures containing peptides and proteins known as toxins, which are responsible for the deleterious effect of envenomations. Across the animal …
Antivenoms are fundamental in the therapy for snakebites. In elapid venoms, there are toxins, eg short-chain α-neurotoxins, which are quite abundant, highly toxic, and …
T Lüddecke, A Paas, RJ Harris, L Talmann… - … in bioengineering and …, 2023 - frontiersin.org
Venoms are complex chemical arsenals that have evolved independently many times in the animal kingdom. Venoms have attracted the interest of researchers because they are an …
The three-fingered toxin family and more precisely short-chain α-neurotoxins (also known as Type I α-neurotoxins) are crucial in defining the elapid envenomation process, but …
JF Guerrero-Garzón, M Bénard-Valle… - Biochimie, 2018 - Elsevier
The three-finger toxins (3FTxs) represent an extremely diverse protein family in elapid venoms, where the short chain α-neurotoxins are the most relevant toxin group from the …
An mRNA transcript that codes for a Disintegrin and a Metalloprotease from a venom gland of the viper Bothrops ammodytoides was isolated. Vector pCR® 2.1-TOPO was used to …
The gene of the four disulfide-bridged defensin J1-1 from Capsicum was cloned into the expression vector pQE30 containing a 6His-tag as fusion protein. This construct was …
Abstract The coralsnake Micrurus dumerilii (Elapidae) is reported to cause envenomings of medical importance. Previous studies characterized the protein composition of its venom …
LE Romero-Giraldo, S Pulido, MA Berrío, MF Flórez… - Toxins, 2022 - mdpi.com
Micrurus dumerilii is a coral snake of clinic interest in Colombia. Its venom is mainly composed of phospholipases A2 being MdumPLA2 the most abundant protein …