Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently
absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a …

Data are accumulating that emphasize the important role of the intestinal barrier and
intestinal permeability for health and disease. However, these terms are poorly defined, their …

Obesity and insulin resistance are associated with chronic inflammation in metabolic tissues
such as adipose tissue and the liver. Recently, growing evidence has implicated the …

The aetiology of obesity has been attributed to several factors (environmental, dietary,
lifestyle, host, and genetic factors); however none of these fully explain the increase in the …

Prolonged high fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and
diets high in saturated fat are a risk factor for the development of human inflammatory bowel …

A hallmark of obesity is chronic low‐grade inflammation, which plays a major role in the
process of atherosclerotic cardiovascular disease (ACVD). Gut microbiota is one of the …

Objective Intestinal microbiota have been suggested to contribute to the development of
obesity, but the mechanism remains elusive. The relationship between microbiota …

The prevalence of obesity and related disorders such as metabolic syndrome has vastly
increased throughout the world. Recent insights have generated an entirely new perspective …

At birth, the human colon is rapidly colonized by gut microbes. Owing to their vast number
and their capacity to ferment nutrients and secrete bioactive compounds, these …