The consumption of sugar has become central to the Western diet. Cost and health concerns
associated with sucrose spurred the development and consumption of other sugars and …

Living organisms such as bacteria are often exposed to continuous changes in the nutrient
availability in nature. Therefore, bacteria must constantly monitor the environmental …

Catabolite repression refers to the process where the metabolism of one sugar represses
the genes involved in metabolizing another sugar. While glucose provides the canonical …

Lignocellulosic biomass, consisting of homo-and heteropolymeric sugars, acts as a
substrate for the generation of valuable biochemicals and biomaterials. The readily …

Background Glycolysis breakdowns glucose into essential building blocks and ATP/NAD (P)
H for the cell, occupying a central role in its growth and bio-production. Among glycolytic …

Highlights•Phenotypic heterogeneity in metabolism is driven by nutrient limitation.•Nutrient
limitation underpins metabolic heterogeneity caused by temporal fluctuations in substrate …

Highlights•The evolution and diversity of metabolic strategies is poorly understood.•Systems
Biology models can predict metabolic strategies from genomic data.•Metabolic strategies …

The bioproduction of xylitol from hemicellulose hydrolysate has good potential for industrial
development. However, xylitol productivity has always been limited due to corncob …

Highlights•Relaxation of catabolite repression (CCR) in Escherichia coli is a major area of
research due to its industrial application.•Recent strategies for relaxation of CCR can be …

Prokaryotic transcription factors can be repurposed into biosensors for the ligand-inducible
control of gene expression, but the landscape of chemical ligands for which biosensors exist …