The brain is a highly metabolically active tissue that critically relies on oxidative
phosphorylation as a means for maintaining energy. One result of this process is the …

Abstract Lipoic acid (α-LA)(1, 2-dithiolane3-pentanoic acid (C8H14O2S2) is also called
thioctic acid with an oxidized (disulfide, LA) and a reduced (di-thiol: dihydro-lipoic acid …

Remote ischemic postconditioning (RIPoC) attenuates ischemia/reperfusion (I/R) injury in
the heart, lung and hind limb. RIPoC performed in the hind limb reduces brain injury …

Huntington's disease (HD) is the most common polyglutamine neurodegenerative disorder
in humans, and is caused by a mutation of an unstable expansion of CAG repeats within the …

Ischemia‐reperfusion (I/R) injury often occurred in some pathologies and surgeries. I/R
injury not only harmed to physiological functions of corresponding organ and tissue but also …

In this study, the possible role of oxidative stress and nitric oxide (NO) synthase isoforms in
the development of morphine tolerance and dependence, and effect of alpha-lipoic acid on …

Objectives: α-lipoic acid (ALA) is a natural antioxidant which acts as a cofactor of
bioenergetic mitochondrial enzymes. Along with its mitochondrial action, ALA and its …

Background/Aims: Alpha-lipoic acid (α-LA) has been demonstrated to be protective against
cerebral ischemia injury. Herein, we investigate the neuroprotective effect and underlying …

Testicular torsion is one of the urologic emergencies occurring frequently in neonatal and
adolescent period. Testis is sensitive to ischemia‐reperfusion injury, and, therefore …

We have previously demonstrated that the administration of low doses of dimethoate,
glyphosate and zineb to rats (ip 1/250 LD50, three times a week for 5weeks) provokes …