[HTML][HTML] Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

K Oliphant, E Allen-Vercoe - Microbiome, 2019 - Springer
The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

[HTML][HTML] The impact of CKD on uremic toxins and gut microbiota

J Rysz, B Franczyk, J Ławiński, R Olszewski… - Toxins, 2021 - mdpi.com
Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

[HTML][HTML] The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease

H Zhu, C Cao, Z Wu, H Zhang, Z Sun, M Wang, H Xu… - Cell metabolism, 2021 - cell.com
The relationship between gut microbial dysbiosis and acute or chronic kidney disease
(CKD) is still unclear. Here, we show that oral administration of the probiotic Lactobacillus …

[HTML][HTML] Interplay between the human gut microbiome and host metabolism

A Visconti, CI Le Roy, F Rosa, N Rossi… - Nature …, 2019 - nature.com
The human gut is inhabited by a complex and metabolically active microbial ecosystem.
While many studies focused on the effect of individual microbial taxa on human health, their …

Inflammation‐related mechanisms in chronic kidney disease prediction, progression, and outcome

S Mihai, E Codrici, ID Popescu… - Journal of …, 2018 - Wiley Online Library
Persistent, low‐grade inflammation is now considered a hallmark feature of chronic kidney
disease (CKD), being involved in the development of all‐cause mortality of these patients …

[HTML][HTML] Cognitive impairment by antibiotic-induced gut dysbiosis: analysis of gut microbiota-brain communication

EE Fröhlich, A Farzi, R Mayerhofer… - Brain, behavior, and …, 2016 - Elsevier
Emerging evidence indicates that disruption of the gut microbial community (dysbiosis)
impairs mental health. Germ-free mice and antibiotic-induced gut dysbiosis are two …

Gut–organ axis: a microbial outreach and networking

S Ahlawat, Asha, KK Sharma - Letters in applied microbiology, 2021 - academic.oup.com
Human gut microbiota (GM) includes a complex and dynamic population of microorganisms
that are crucial for well‐being and survival of the organism. It has been reported as diverse …

[HTML][HTML] Oxidative stress markers in chronic kidney disease with emphasis on diabetic nephropathy

N Vodošek Hojs, S Bevc, R Ekart, R Hojs - Antioxidants, 2020 - mdpi.com
Diabetes prevalence is increasing worldwide, especially through the increase of type 2
diabetes. Diabetic nephropathy occurs in up to 40% of diabetic patients and is the leading …

Synbiotics easing renal failure by improving gut microbiology (SYNERGY): a randomized trial

M Rossi, DW Johnson, M Morrison… - Clinical Journal of the …, 2016 - journals.lww.com
Results Of 37 individuals randomized (age= 69±10 years old; 57% men; eGFR= 24±8
ml/min per 1.73 m 2), 31 completed the study. Synbiotic therapy did not significantly reduce …

Role of the gut microbiome in uremia: a potential therapeutic target

A Ramezani, ZA Massy, B Meijers, P Evenepoel… - American Journal of …, 2016 - Elsevier
Also known as the “second human genome,” the gut microbiome plays important roles in
both the maintenance of health and the pathogenesis of disease. The symbiotic relationship …