Aims To evaluate the impact of galangin treatment on cerebral ischemia-reperfusion (I/R)
injury in gerbils and to identify potential mechanisms of the protective effect of galangin on …

The nuclear factor erythroid-derived 2-related factor 2 (NFE2L2/Nrf2) is a pivotal facilitator of
cytoprotective responses against the oxidative/electrophilic insults. Upon activation, Nrf2 …

Increased expression of endothelin (ET) peptide and its receptors following ischemic stroke
is found to regulate many critical aspects of stroke pathophysiology. Many attempts have …

Cryopreservation of stallion semen has not reached the level of efficiency and positive
results described in other species. This is mainly due to the greater sensitivity of stallion …

Reactive oxygen species contribute to the development of various human diseases.
Ischemia is characterized by both significant oxidative stress and characteristic changes in …

Background Statins such as simvastatin are inhibitors of 3-hydroxy-3-methylglutaryl-
coenzyme A (HMG-CoA) reductase used in the prevention of cardiovascular disease. In …

Neuronal loss (death) occurs selectively in vulnerable brain regions after ischemic insults.
Astrogliosis is accompanied by neuronal death. It can change the molecular expression and …

Hemorrhagic transformation is an important complication of acute ischemic stroke,
particularly in diabetic patients receiving thrombolytic treatment with tissue plasminogen …

We investigated the probability of newly generated neurons that could survive and mature in
the ischemic hippocampal CA1 region (CA1) of a gerbil model of transient cerebral …

Hemoglobin (Hb) is a major constituent of blood and a potent mediator of oxidative or
nitrative stress after intracerebral hemorrhage (ICH). Our previous study demonstrated that …