Protein kinases regulate nearly all aspects of cell life, and alterations in their expression, or
mutations in their genes, cause cancer and other diseases. Here, we review the remarkable …

Circulating tumor DNA (ctDNA), ie, DNA shed from tumor cells into the bloodstream, is
emerging as one of the most useful plasma biomarkers in patients with multiple types of …

Immunotherapy for metastasized non‐small‐cell lung cancer (NSCLC) can show long‐
lasting clinical responses. Selection of patients based on programmed death‐ligand 1 (PD …

Vascular endothelial growth factor inhibitors, including tyrosine kinase inhibitors (TKIs),
possess immunomodulatory properties and have shown promising outcomes when …

This systematic review with embedded meta-analysis aimed to evaluate the clinical utility of
circulating tumor DNA (ctDNA) in lung cancer. After screening and review of the Embase …

The neurotrophic receptor tyrosine kinase (NTRK) family of genes, including NTRK1,
NTRK2, and NTRK3, encodes membrane-bound receptors that normally regulate cell …

Kirsten rat sarcoma viral oncogene homolog (KRAS) gene encodes a GTPase that acts as a
molecular switch for intracellular signal transduction, promoting cell growth and proliferation …

Simple Summary An early assessment of response to treatment is crucial to informing
appropriate therapeutic management. Using a plasma-only strategy, we measured changes …

Non-small cell cancer (NSCLC) has been identified with a great variation of mutations that
can be surveyed during disease progression. The aim of the study was to identify and …

Purpose: The clinical potential of liquid biopsy in patients with advanced cancer is real-time
monitoring for early detection of treatment failure. Our study aimed to investigate the clinical …