The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro
surrogate of a biological system. For the results and outputs from this research to be …

Stem cells offer new therapeutic avenues for the repair and replacement of damaged tissues
and organs owing to their self-renewal and multipotent differentiation capabilities. In this …

To survey cancer-related mutations in human pluripotent stem cells and their derivatives, we
analyzed> 2,200 transcriptomes from 146 independent lines in the NCBI's Sequence Read …

Culture-acquired variants in human pluripotent stem cells (hPSCs) hinder their applications
in research and clinic. However, the mechanisms that underpin selection of variants remain …

Stem cells exist in vitro in a spectrum of interconvertible pluripotent states. Analyzing
hundreds of hiPSCs derived from different individuals, we show the proportions of these …

Genetic alterations are often acquired during prolonged propagation of pluripotent stem
cells (PSCs). This ruins the stem cell quality and hampers their full applications …

Age-related macular degeneration (AMD) is the leading cause of blindness in individuals
over the age of 50 years, yet its etiology and pathogenesis largely remain uncovered. Single …

Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular
heterogeneity and the dynamics of gene expression, bearing profound significance in stem …

Background: This study aimed to conduct a bibliometric analysis of the literature on stem cell
therapy for spinal cord injury to visualize the research status, identify hotspots, and explore …

Background Induced pluripotent stem cell (iPSC)-derived cell therapies are an interesting
new area in the field of regenerative medicine. One of the approaches to decrease the costs …