Annual research review: childhood maltreatment, latent vulnerability and the shift to preventative psychiatry–the contribution of functional brain imaging
Background Childhood maltreatment is a potent predictor of poor mental health across the
life span. We argue that there is a need to improve the understanding of the mechanisms …
life span. We argue that there is a need to improve the understanding of the mechanisms …
Neural contributors to trauma resilience: a review of longitudinal neuroimaging studies
Resilience in the face of major life stressors is changeable over time and with experience.
Accordingly, differing sets of neurobiological factors may contribute to an adaptive stress …
Accordingly, differing sets of neurobiological factors may contribute to an adaptive stress …
[HTML][HTML] The ecology of human fear: survival optimization and the nervous system
We propose a Survival Optimization System (SOS) to account for the strategies that humans
and other animals use to defend against recurring and novel threats. The SOS attempts to …
and other animals use to defend against recurring and novel threats. The SOS attempts to …
Adolescent friendships predict later resilient functioning across psychosocial domains in a healthy community cohort
BackgroundAdolescence is a key time period for the emergence of psychosocial and mental
health difficulties. To promote adolescent adaptive ('resilient') psychosocial functioning …
health difficulties. To promote adolescent adaptive ('resilient') psychosocial functioning …
Maternal systemic interleukin-6 during pregnancy is associated with newborn amygdala phenotypes and subsequent behavior at 2 years of age
Background Maternal inflammation during pregnancy increases the risk for offspring
psychiatric disorders and other adverse long-term health outcomes. The influence of …
psychiatric disorders and other adverse long-term health outcomes. The influence of …
Childhood maltreatment is associated with altered fear circuitry and increased internalizing symptoms by late adolescence
RJ Herringa, RM Birn, PL Ruttle… - Proceedings of the …, 2013 - National Acad Sciences
Maltreatment during childhood is a major risk factor for anxiety and depression, which are
major public health problems. However, the underlying brain mechanism linking …
major public health problems. However, the underlying brain mechanism linking …
The theory of latent vulnerability: Reconceptualizing the link between childhood maltreatment and psychiatric disorder
EJ McCrory, E Viding - Development and psychopathology, 2015 - cambridge.org
Maltreatment in childhood is associated with a significantly increased likelihood of
psychiatric disorder that endures across the life span. If disorders emerge they tend to be …
psychiatric disorder that endures across the life span. If disorders emerge they tend to be …
[HTML][HTML] Heightened neural reactivity to threat in child victims of family violence
Exposure to family violence affects a significant minority of children: estimates of physical
abuse range from 4 to 16%, while intimate partner violence affects between 8 and 25% of …
abuse range from 4 to 16%, while intimate partner violence affects between 8 and 25% of …
[HTML][HTML] The role of habit in compulsivity
Compulsivity has been recently characterized as a manifestation of an imbalance between
the brain׳ s goal-directed and habit-learning systems. Habits are perhaps the most …
the brain׳ s goal-directed and habit-learning systems. Habits are perhaps the most …
A causal model of post-traumatic stress disorder: disentangling predisposed from acquired neural abnormalities
Discriminating neural abnormalities into the causes versus consequences of
psychopathology would enhance the translation of neuroimaging findings into clinical …
psychopathology would enhance the translation of neuroimaging findings into clinical …