Oxidative stress pathways in pancreatic β-cells and insulin-sensitive cells and tissues: importance to cell metabolism, function, and dysfunction

P Newsholme, KN Keane… - American Journal of …, 2019 - journals.physiology.org
It is now accepted that nutrient abundance in the blood, especially glucose, leads to the
generation of reactive oxygen species (ROS), ultimately leading to increased oxidative …

Micronutrients impact the gut microbiota and blood glucose

NG Barra, FF Anhê, JF Cavallari… - Journal of …, 2021 - joe.bioscientifica.com
Micronutrients influence hormone action and host metabolism. Dietary minerals, trace
elements, and vitamins can alter blood glucose and cellular glucose metabolism, and …

KDOQI clinical practice guideline for nutrition in CKD: 2020 update

TA Ikizler, JD Burrowes, LD Byham-Gray… - American Journal of …, 2020 - Elsevier
Abstract The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative
(KDOQI) has provided evidence-based guidelines for nutrition in kidney diseases since …

Association between exposure to arsenic, nickel, cadmium, selenium, and zinc and fasting blood glucose levels

Z Li, Y Xu, Z Huang, Y Wei, J Hou, T Long, F Wang… - Environmental …, 2019 - Elsevier
Associations between single metal and fasting blood glucose (FBG) levels have been
reported in previous studies. However, the association between multi-metals exposure and …

Association between cortisol, insulin resistance and zinc in obesity: a mini-review

JBS Morais, JS Severo, JB Beserra… - Biological trace element …, 2019 - Springer
Adipose tissue is considered an endocrine organ and its excess compromises the immune
response and the metabolism of hormones and nutrients. Furthermore, visceral fat …

Zinc supplementation alleviates lipid and glucose metabolic disorders induced by a high-fat diet

Y Qi, Z Zhang, S Liu, Z Aluo, L Zhang, L Yu… - Journal of agricultural …, 2020 - ACS Publications
Zinc deficiency is a risk factor for the development of obesity and diabetes. Studies have
shown lower serum zinc levels in obese individuals and those with diabetes. We speculate …

Inside the insulin secretory granule

M Germanos, A Gao, M Taper, B Yau, MA Kebede - Metabolites, 2021 - mdpi.com
The pancreatic β-cell is purpose-built for the production and secretion of insulin, the only
hormone that can remove glucose from the bloodstream. Insulin is kept inside miniature …

Investigating the role of zinc in atherosclerosis: a review

T Shen, Q Zhao, Y Luo, T Wang - Biomolecules, 2022 - mdpi.com
Zinc, an indispensable micronutrient for human health, might play an important role in the
development of atherosclerosis. Zinc could be involved in the atherogenic process through …

Zinc homeostasis in diabetes mellitus and vascular complications

S MacKenzie, A Bergdahl - Biomedicines, 2022 - mdpi.com
Oxidative stress represents an impaired metabolic system that promotes damage to cells
and tissues. This is the predominant factor that leads to the development and progression of …

Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin-resistant women: impact on MAPK and NFκB signaling …

VC Capetini, BJ Quintanilha, DC de Oliveira… - The Journal of …, 2023 - Elsevier
Blood orange consumption presents potential health benefits and may modulate epigenetic
mechanisms such as microRNAs (miRNAs) expression. MiRNAs are non-coding RNAs …