Chronic immune activation is one of the hallmarks of human immunodeficiency virus (HIV)
infection. It is present also, with very similar characteristics, in very large human populations …

The progression towards AIDS in HIV-1-infected individuals appears to be directly related to
CD4 cell count decline and HIV-1 viral loads in the plasma and lymphoid tissues [1]. Though …

Significant quantities of PGE 2 were produced by cercariae of Schistosoma mansoni
following incubation with linoleic acid, a free fatty acid found on the surface of the skin …

Despite effective chemotherapy to treat schistosome infections, re-infection rates are
extremely high. Resistance to reinfection can develop, however it typically takes several …

Human echinococcosis is one of the world's major zoonotic infections. In this study, our aim
is to clarify one of the strategies used by the parasite for evasion and prolonged infestation …

In schistosomiasis mansoni, parasite eggs precipitate an intrahepatic granulomatous and
fibrosing inflammatory process, which is mediated by, and dependent on, MHC class II …

Multiple exposures of chimpanzees to the radiation-attenuated schistosome vaccine
provoked a strong parasite-specific cellular and humoral immune response. Specific IgM …

Schistosoma mansoni infection has been associated with protection against allergies. The
mechanisms underlying this association may involve regulatory cells and cytokines. We …

Pathogenesis of chronically developing alveolar echinococcosis (AE) is characterized by a
continuous, granulomatous, periparasitic infiltration of immune cells surrounding the …

Acquired immunity against helminths is characterised by a complex interplay between the
effector Th1 and Th2 immune responses and it slowly manifests with age as a result of …