Pyrazolopyrimidinone compounds and uses thereof
CO Ndubaku, GE Katibah, TC Roberts, L Sung… - US Patent …, 2020 - Google Patents
2018-11-26 Assigned to Aduro Biotech, Inc. reassignment Aduro Biotech, Inc. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NDUBAKU …
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NDUBAKU …
Inhibitors of receptor interacting protein kinase I for the treatment of disease
RT Lewis, M Hamilton, WJ Ray, F Alvarez… - US Patent …, 2023 - Google Patents
US11690850B2 - Inhibitors of receptor interacting protein kinase I for the treatment of disease
- Google Patents US11690850B2 - Inhibitors of receptor interacting protein kinase I for the …
- Google Patents US11690850B2 - Inhibitors of receptor interacting protein kinase I for the …
RIP1 inhibitory compounds and methods for making and using the same
J Yu, I Darwish, V Taylor, R Kolluri, Y Chen… - US Patent …, 2023 - Google Patents
Provisional application No. 63/004319, filed on Apr. 2, 2020, provisional application No.
63/004,290, filed on Apr. 2, 2020, provisional application No. 63/001,016, filed on Mar. 27 …
63/004,290, filed on Apr. 2, 2020, provisional application No. 63/001,016, filed on Mar. 27 …
Inhibitors of receptor interacting protein kinase I for the treatment of disease
RT Lewis, MM Hamilton, WJ Ray, F Alvarez… - US Patent …, 2023 - Google Patents
US11753381B2 - Inhibitors of receptor interacting protein kinase I for the treatment of disease
- Google Patents US11753381B2 - Inhibitors of receptor interacting protein kinase I for the …
- Google Patents US11753381B2 - Inhibitors of receptor interacting protein kinase I for the …
Tri-cycle compound and applications thereof
H He, J Wang, Z Jiang, Y Yaxun, P Shao… - US Patent …, 2021 - Google Patents
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- Tri-cycle compound and applications thereof - Google Patents Tri-cycle compound and …
- Tri-cycle compound and applications thereof - Google Patents Tri-cycle compound and …
RIP1 inhibitory compounds and methods for making and using the same
E Masuda, S Shaw, V Taylor, S Bhamidipati - US Patent 12,116,354, 2024 - Google Patents
US12116354B2 - RIP1 inhibitory compounds and methods for making and using the same -
Google Patents US12116354B2 - RIP1 inhibitory compounds and methods for making and using …
Google Patents US12116354B2 - RIP1 inhibitory compounds and methods for making and using …
Crystal form of tri-cycle compound and application thereof
J Wang, Z Jiang, H He, Y Yaxun - US Patent 11,952,388, 2024 - Google Patents
US11952388B2 - Crystal form of tri-cycle compound and application thereof - Google
Patents US11952388B2 - Crystal form of tri-cycle compound and application thereof …
Patents US11952388B2 - Crystal form of tri-cycle compound and application thereof …
Inhibitors of receptor interacting protein kinase I for the treatment of disease
RT Lewis, M Hamilton, WJ Ray, F Alvarez… - US Patent …, 2023 - Google Patents
US11718612B2 - Inhibitors of receptor interacting protein kinase I for the treatment of disease
- Google Patents US11718612B2 - Inhibitors of receptor interacting protein kinase I for the …
- Google Patents US11718612B2 - Inhibitors of receptor interacting protein kinase I for the …
Treatment of necroptosis
R Jalan, F Andreola, S MacDonald… - US Patent 11,714,087, 2023 - Google Patents
The present invention derives from the unexpected finding that necroptosis is a novel
biomarker and target for therapy in patients with liver failure such as acute liver failure (ALF) …
biomarker and target for therapy in patients with liver failure such as acute liver failure (ALF) …