Heterocyclic compounds are inevitable in a numerous part of life sciences. These molecules
perform various noteworthy functions in nature, medication and innovation. Nitrogen …

Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

Clinically significant antibiotic resistance is one of the greatest challenges of the twenty‐first
century. However, new antibacterial agents are currently being developed at a much slower …

The continuous emergence and rapid spread of a multidrug-resistant strain of bacterial
pathogens have demanded the discovery and development of new antibacterial agents. A …

Drug-resistant tuberculosis (TB) poses a significant challenge to the successful treatment
and control of TB worldwide. Resistance to anti-TB drugs has existed since the beginning of …

Similar to its eukaryotic counterpart, the prokaryotic cytoskeleton is essential for the
structural and mechanical properties of bacterial cells. The essential protein FtsZ is a central …

The disturbing increase in the number of bacterial pathogens that are resistant to multiple, or
sometimes all, current antibiotics highlights the desperate need to pursue the discovery and …

Salmonella Typhi is emerging as a drug-resistant pathogen, particularly in developing
countries. Hence, the progressive development of new antibiotics against novel drug targets …

Heterocyclic compounds are significant lead drug candidates based on their various
structure–activity relationships (SAR), and their use in pharmaceutics is constantly …