Approaches to study gap junctional coupling

J Stephan, S Eitelmann, M Zhou - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Astrocytes and oligodendrocytes are main players in the brain to ensure ion and
neurotransmitter homeostasis, metabolic supply, and fast action potential propagation in …

On the electrical passivity of astrocyte potassium conductance

M Zhou, Y Du, S Aten… - Journal of …, 2021 - journals.physiology.org
Predominant expression of leak-type K+ channels provides astrocytes a high membrane
permeability to K+ ions and a hyperpolarized membrane potential that are crucial for …

Properties of REM sleep alterations with epilepsy

Y Ikoma, Y Takahashi, D Sasaki, K Matsui - Brain, 2023 - academic.oup.com
It is usually assumed that individuals rest during sleep. However, coordinated neural activity
that presumably requires high energy consumption is increased during REM sleep. Here …

Chronic stress impairs the structure and function of astrocyte networks in an animal model of depression

S Aten, Y Du, O Taylor, C Dye, K Collins… - Neurochemical …, 2023 - Springer
Now astrocytes appear to be the key contributors to the pathophysiology of major
depression. Evidence in rodents shows that chronic stress is associated with a decreased …

Exacerbation of epilepsy by astrocyte alkalization and gap junction uncoupling

M Onodera, J Meyer, K Furukawa… - Journal of …, 2021 - Soc Neuroscience
Seizures invite seizures. At the initial stage of epilepsy, seizures intensify with each episode;
however, the mechanisms underlying this exacerbation remain to be solved. Astrocytes …

Genesis of a functional astrocyte syncytium in the developing mouse hippocampus

S Zhong, CM Kiyoshi, Y Du, W Wang, Y Luo, X Wu… - Glia, 2023 - Wiley Online Library
Astrocytes are increasingly shown to operate as an isopotential syncytium in brain function.
Protoplasmic astrocytes acquire this ability to functionally go beyond the single‐cell level by …

The role of polyamines in the mechanisms of cognitive impairment

MG Makletsova, GT Rikhireva, EY Kirichenko… - Neurochemical …, 2022 - Springer
As the population ages, age-related cognitive impairments are becoming an increasingly
pressing problem. Currently, the role of polyamines (putrescine, spermidine, and spermine) …

Structure and functions of gap junctions and their constituent connexins in the mammalian CNS

EY Kirichenko, SN Skatchkov, AM Ermakov - … Moscow), Supplement Series …, 2021 - Springer
Numerous data obtained in the last 20 years indicate that all parts of the mature central
nervous system, from the retina and olfactory bulb to the spinal cord and brain, contain cells …

[图书][B] Cellular Signaling Events Serving at the Interface of Cognition, Stress, and Circadian Clock Entrainment

S Aten - 2021 - search.proquest.com
Cellular signaling events are integral processes that govern the activity of cells throughout
the body and help coordinate key physiological and behavioral processes within organisms …

Back to Basics: A Role for Astrocyte Alkalization in Epileptogenesis

JL Wagnon - Epilepsy Currents, 2021 - journals.sagepub.com
Exacerbation of Epilepsy by Astrocyte Alkalization and Gap Junction Uncoupling Onodera
M, Meyer J, Furukawa K, et al. J Neurosci. 2021; 41 (10): 2106-2118. Seizures invite …