Functional, immunological and three-dimensional analysis of chemically synthesised sporozoite peptides as components of a fully-effective antimalarial vaccine

H Curtidor, M Vanegas, MP Alba… - Current medicinal …, 2011 - ingentaconnect.com
Our ongoing search for a fully-effective vaccine against the Plasmodium falciparum parasite
(causing the most lethal form of human malaria) has been focused on identifying and …

A conserved apicomplexan microneme protein contributes to Toxoplasma gondii invasion and virulence

MH Huynh, MJ Boulanger, VB Carruthers - Infection and immunity, 2014 - Am Soc Microbiol
The obligate intracellular parasite Toxoplasma gondii critically relies on host cell invasion
during infection. Proteins secreted from the apical micronemes are central components for …

The Impact of Geographical Variation in Plasmodium knowlesi Apical Membrane Protein 1 (PkAMA-1) on Invasion Dynamics of P. knowlesi

YL Ng, WC Lee, YL Lau, MY Fong - Tropical medicine and infectious …, 2023 - mdpi.com
Plasmodium knowlesi has emerged as an important zoonotic parasite that causes persistent
symptomatic malaria in humans. The signs and symptoms of malaria are attributed to the …

Secreted protein with altered thrombospondin repeat (SPATR) is essential for asexual blood stages but not required for hepatocyte invasion by the malaria parasite …

R Gupta, A Mishra, HH Choudhary… - Molecular …, 2020 - Wiley Online Library
Upon entering its mammalian host, the malaria parasite productively invades two distinct cell
types, that is, hepatocytes and erythrocytes during which several adhesins/invasins are …

Synthetic peptides from two Pf sporozoite invasion-associated proteins specifically interact with HeLa and HepG2 cells

G Arévalo-Pinzón, H Curtidor, M Muñoz, MA Patarroyo… - Peptides, 2011 - Elsevier
Two recently described molecules have been associated with sporozoite traversal ability
and hepatocyte entry: sporozoite invasion-associated proteins (SIAP)-1 and-2. The HeLa …

[PDF][PDF] Genetic diversity of secreted protein with an altered thrombospondin repeat (SPATR) of Plasmodium knowlesi clinical isolates from Malaysia.

UW Azlan, YL Lau, MHA Hamid, J Jelip, CH Ooi… - 2022 - msptm.org
The Plasmodium knowlesi secreted protein with an altered thrombospondin repeat
(PkSPATR) is an important protein that helps in the parasite's invasion into the host cell. This …

Binding activity, structure, and immunogenicity of synthetic peptides derived from Plasmodium falciparum CelTOS and TRSP proteins

H Curtidor, G Arévalo-Pinzón, A Bermudez, D Calderon… - Amino acids, 2012 - Springer
Several sporozoite proteins have been associated with Plasmodium falciparum cell traversal
and hepatocyte invasion, including the cell-traversal protein for ookinetes and sporozoites …

[PDF][PDF] RESEARCH ARTICLE Inhibition of Plasmodium knowlesimerozoite invasion into human erythrocytes by antibodies raised against the parasite's secreted …

UW Azlan, FW Cheong, YL Lau, MY Fong - Tropical Biomedicine, 2024 - msptm.org
The Plasmodium secreted protein with an altered thrombospondin repeat (SPATR) has
been known to play an important role in the malaria parasite's invasion into host …

Well-Defined Regions of the Plasmodium falciparum Reticulocyte Binding Protein Homologue 4 Mediate Interaction with Red Blood Cell Membrane

J García, H Curtidor, CG Pinzón… - Journal of medicinal …, 2010 - ACS Publications
Two widely studied parasite protein families are considered attractive targets for developing
a fully effective antimalarial vaccine: the erythrocyte binding antigen (EBA) family defining a …

Dos fragmentos recombinantes derivados de la proteína secretada con dominio de repetición de trombospondina alterado (SPATR) de Plasmodium vivax interactúan …

AF Cárdenas Carpeta - 2022 - repositorio.uan.edu.co
El ciclo de invasión de Plasmodium al ser humano involucra un alto número de proteínas
que le permiten interactuar e invadir a las células hospederas. Recientes estudios en …