Tackling current production of HAp and HAp-driven biomaterials

A Veiga, S Madureira, JB Costa, F Castro… - Materials …, 2023 - pubs.rsc.org
Hydroxyapatite (HAp)-based biomaterials are well-established for biomedical applications
due to their extensive research work and clinical track record. Recent efforts have been …

Bioactive scaffolds as a promising alternative for enhancing critical-size bone defect regeneration in the craniomaxillofacial region

SA Bello, J Cruz-Lebrón… - ACS Applied Bio …, 2023 - ACS Publications
Reconstruction of critical-size bone defects (CSDs) in the craniomaxillofacial (CMF) region
remains challenging. Scaffold-based bone-engineered constructs have been proposed as …

Multi-leveled nanosilicate implants can facilitate near-perfect bone healing

M Keshavarz, P Alizadeh, FB Kadumudi… - … Applied Materials & …, 2023 - ACS Publications
Several studies have shown that nanosilicate-reinforced scaffolds are suitable for bone
regeneration. However, hydrogels are inherently too soft for load-bearing bone defects of …

[HTML][HTML] Phase composition of calcium phosphate materials affects bone formation by modulating osteoclastogenesis

P Humbert, C Kampleitner, J De Lima, MÁ Brennan… - Acta biomaterialia, 2024 - Elsevier
Human mesenchymal stromal cells (hMSCs) seeded on calcium phosphate (CaP)
bioceramics are extensively explored in bone tissue engineering and have recently shown …

Engineered nanostructure fibrous cell-laden biointerfaces integrating Fe3O4/SrO2-fMWCNTs induce osteogenesis and anti-bacterial effect

R Kandel, SR Jang, U Ghimire, S Shrestha… - Journal of Industrial and …, 2023 - Elsevier
Improving biomechanical and biochemical properties of tissue-engineered scaffolds akin to
those of native stem-cell niches can effectively regenerate tissues. Bio-ceramic …

[HTML][HTML] Current status of nano-embedded growth factors and stem cells delivery to bone for targeted repair and regeneration

W Liang, C Zhou, X Liu, Q Xie, L Xia, L Liu… - Journal of Orthopaedic …, 2025 - Elsevier
Bone-related diseases like osteoarthritis and osteoporosis impact millions globally, affecting
quality of life. Osteoporosis considerably enhances the probability of bone fractures of the …

Engineered 3D-printed polyvinyl alcohol scaffolds incorporating β-tricalcium phosphate and icariin induce bone regeneration in rat skull defect model

Z Xu, Y Sun, H Dai, Y Ma, H Bing - Molecules, 2022 - mdpi.com
The skull defects are challenging to self-heal, and autologous bone graft repair has
numerous drawbacks. The scaffolds for the rapid and effective repair of skull defects have …

A narrative review of cell-based approaches for cranial bone regeneration

MI Falguera Uceda, S Sánchez-Casanova… - Pharmaceutics, 2022 - mdpi.com
Current cranial repair techniques combine the use of autologous bone grafts and
biomaterials. In addition to their association with harvesting morbidity, autografts are often …

An empirical model linking physico-chemical biomaterial characteristics to intra-oral bone formation

E Sadeghian Dehkord, G Kerckhofs… - Journal of Functional …, 2023 - mdpi.com
Facial trauma, bone resection due to cancer, periodontal diseases, and bone atrophy
following tooth extraction often leads to alveolar bone defects that require bone regeneration …

Osteogenic property regulation of stem cells by a hydroxyapatite 3D-hybrid scaffold with cancellous bone structure

H Xia, L Dong, M Hao, Y Wei, J Duan, X Chen… - Frontiers in …, 2021 - frontiersin.org
Cancellous bone plays an indispensable role in the skeletal system due to its various
functions and high porosity. In this work, chitosan and hydroxyapatite nanowires (CS@ HAP …