[HTML][HTML] Evaluation of novel fetal hemoglobin inducer drugs in treatment of β-hemoglobinopathy disorders
AD Fard, SA Hosseini, M Shahjahani… - … journal of hematology …, 2013 - ncbi.nlm.nih.gov
Objective The use of fetal hemoglobin (HbF) inducer drugs is considered as a novel
approach in treatment of β-hemoglobinopathies, especially β-thalassemia and sickle cell …
approach in treatment of β-hemoglobinopathies, especially β-thalassemia and sickle cell …
[HTML][HTML] MicroRNA expression in β-thalassemia and sickle cell disease: a role in the induction of fetal hemoglobin
Today the regulatory role of microRNAs (miRs) is well characterized in many diverse cel-
lular processes. MiR-based regulation is categorized under epigenetic regulatory mecha …
lular processes. MiR-based regulation is categorized under epigenetic regulatory mecha …
[HTML][HTML] Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia
NH Eltaweel, GY ElKamah, R Khairat, HAE Atia… - Journal of Genetic …, 2021 - Elsevier
Abstract Background Fetal hemoglobin (HbF) induction has shown promise for the treatment
of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective …
of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective …
Hemoglobin F (HbF) inducers; history, structure and efficacies
Z Hashemi, MA Ebrahimzadeh - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
Inherited beta-thalassemia is caused by irregular production of hemoglobin through
reducing beta-globin chains. It has been observed that increasing fetal hemoglobin (HbF) …
reducing beta-globin chains. It has been observed that increasing fetal hemoglobin (HbF) …
[HTML][HTML] Evaluation of signaling pathways involved in γ-globin gene induction using fetal hemoglobin inducer drugs
F Rahim, H Allahmoradi, F Salari… - … journal of hematology …, 2013 - ncbi.nlm.nih.gov
Potent induction of fetal hemoglobin (HbF) production results in alleviating the complications
of β-thalassemia and sickle cell disease (SCD). HbF inducer agents can trigger several …
of β-thalassemia and sickle cell disease (SCD). HbF inducer agents can trigger several …
[HTML][HTML] Thalidomide is more efficient than sodium butyrate in enhancing GATA-1 and EKLF gene expression in erythroid progenitors derived from HSCs with β-globin …
MAJ Far, AD Fard, S Hajizamani… - … journal of hematology …, 2016 - ncbi.nlm.nih.gov
Background: Efficient induction of fetal hemoglobin (HbF) is considered as an effective
therapeutic approach in beta thalassemia. HbF inducer agents can induce the expression of …
therapeutic approach in beta thalassemia. HbF inducer agents can induce the expression of …
Retrospective study of the incidence of portal vein thrombosis after splenectomy in hematological disorders: Risk factors and clinical presentation
A Sabbagh, B Keikhaei, M Joorabian… - Blood Cells, Molecules …, 2019 - Elsevier
Objective Portal vein thrombosis (PVT) has been described as a rare complication after
splenectomy. PVT associated risk factors after splenectomy in hematological disorders are …
splenectomy. PVT associated risk factors after splenectomy in hematological disorders are …
[HTML][HTML] The role of epigenetics in the induction of fetal hemoglobin: a combination therapy approach
M Ahmadvand, M Noruzinia, AD Fard… - … journal of hematology …, 2014 - ncbi.nlm.nih.gov
The Role of Epigenetics in the Induction of Fetal Hemoglobin: A Combination Therapy Approach
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …
The expression of BCL11A, KLF1, and ERK of mitogen-activated protein kinase pathway on stem cell factor and erythropoietin-treated K562 cells
YSMA Za'ror, Z Zulkafli, LN Al-Eitan… - Biomedical and …, 2022 - journals.lww.com
Background: Currently, the high expression of fetal hemoglobin (HbF) in sickle cell disease
is treated by hydroxyurea (HU). However, potential adverse effect regarding the use of HU is …
is treated by hydroxyurea (HU). However, potential adverse effect regarding the use of HU is …
Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and …
Background Human erythropoiesis is characterized by distinct gene expression profiles at
various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin …
various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin …