SMAD proteins in TGF-β signalling pathway in cancer: regulatory mechanisms and clinical applications

Q Wang, F Xiong, G Wu, D Wang, W Liu, J Chen, Y Qi… - Diagnostics, 2023 - mdpi.com
Suppressor of mother against decapentaplegic (SMAD) family proteins are central to one of
the most versatile cytokine signalling pathways in metazoan biology, the transforming …

Predictive and prognostic value of oncogene mutations and microsatellite instability in locally-advanced rectal cancer treated with neoadjuvant radiation-based …

E De Mattia, J Polesel, S Mezzalira, E Palazzari… - Cancers, 2023 - mdpi.com
Simple Summary Identification of novel molecular markers of pathological complete
response (pCR) to preoperative radiation-based therapy in locally advanced rectal cancer …

MicroRNA-19b Plays a Key Role in 5-Fluorouracil Resistance and Predicts Tumor Progression in Locally Advanced Rectal Cancer Patients

A Santos, I Cristóbal, J Rubio, C Caramés… - International Journal of …, 2022 - mdpi.com
The standard clinical management of locally advanced rectal cancer (LARC) patients
includes neoadjuvant 5-fluorouracil (5-FU)-based chemoradiotherapy (CRT) followed by …

Transcriptomic data analysis coupled with copy number aberrations reveals a blood-based 17-gene signature for diagnosis and prognosis of patients with colorectal …

IH Kaya, O Al-Harazi, D Colak - Frontiers in genetics, 2023 - frontiersin.org
Background: Colorectal cancer (CRC) is the third most common cancer and third leading
cause of cancer-associated deaths worldwide. Diagnosing CRC patients reliably at an early …