Free radical as a double-edged sword in disease: Deriving strategic opportunities for nanotherapeutics

L Zhu, M Luo, Y Zhang, F Fang, M Li, F An… - Coordination chemistry …, 2023 - Elsevier
Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials

Y Zhu, T Zhao, M Liu, S Wang, S Liu, Y Yang, Y Yang… - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

Magnesium galvanic cells produce hydrogen and modulate the tumor microenvironment to inhibit cancer growth

N Yang, F Gong, B Liu, Y Hao, Y Chao, H Lei… - Nature …, 2022 - nature.com
Hydrogen can be used as an anti-cancer treatment. However, the continuous generation of
H2 molecules within the tumor is challenging. Magnesium (Mg) and its alloys have been …

Drug-free antimicrobial nanomotor for precise treatment of multidrug-resistant bacterial infections

L Liu, S Li, K Yang, Z Chen, Q Li, L Zheng, Z Wu… - Nano …, 2023 - ACS Publications
Manufacturing heteronanostructures with specific physicochemical characteristics and tightly
controllable designs is very appealing. Herein, we reported NIR-II light-driven dual …

Radicals scavenging MOFs enabling targeting delivery of siRNA for rheumatoid arthritis therapy

L Guo, S Zhong, P Liu, M Guo, J Ding, W Zhou - Small, 2022 - Wiley Online Library
Macrophages play essential roles in the progression of rheumatoid arthritis (RA), which are
polarized into the pro‐inflammatory M1 phenotype with significant oxidative stress and …

Magnetic nanorobots as maneuverable immunoassay probes for automated and efficient enzyme linked immunosorbent assay

Y Wang, X Liu, C Chen, Y Chen, Y Li, H Ye, B Wang… - ACS …, 2022 - ACS Publications
As a typical, classical, but powerful biochemical sensing technology in analytical chemistry,
enzyme-linked immunosorbent assay (ELISA) shows excellence and wide practicability for …

Arthritic microenvironment actuated nanomotors for active rheumatoid arthritis therapy

C Xu, Y Jiang, H Wang, Y Zhang, Y Ye, H Qin… - Advanced …, 2023 - Wiley Online Library
Increasing O2 demand and excessive ROS production are the main features of arthritic
microenvironment in rheumatoid arthritis (RA) joints and further play pivotal roles in …

Advances in chemically powered micro/nanorobots for biological applications: a review

Y Feng, M An, Y Liu, MT Sarwar… - Advanced Functional …, 2023 - Wiley Online Library
Micro/nanorobots (MNRs) are capable of autonomous motion, breaking through the
limitations of traditional passive transport of nanocarriers. Among them, chemically driven …

[HTML][HTML] Medical micro-and nanomotors in the body

H Li, F Peng, X Yan, C Mao, X Ma, DA Wilson… - … Pharmaceutica Sinica B, 2023 - Elsevier
Attributed to the miniaturized body size and active mobility, micro-and nanomotors (MNMs)
have demonstrated tremendous potential for medical applications. However, from bench to …

Biodegradable magnesium phosphates in biomedical applications

X Gu, Y Li, C Qi, K Cai - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
As an essential element, magnesium is involved in a variety of physiological processes.
Magnesium is the second most abundant cation in cells and the fourth most abundant cation …