COVID-19, blood lipid changes, and thrombosis

AA Farooqui, T Farooqui, GY Sun, TN Lin, DBL Teh… - Biomedicines, 2023 - mdpi.com
Although there is increasing evidence that oxidative stress and inflammation induced by
COVID-19 may contribute to increased risk and severity of thromboses, the underlying …

Citicoline and COVID-19-related cognitive and other neurologic complications

Y Turana, M Nathaniel, R Shen, S Ali, RR Aparasu - Brain sciences, 2021 - mdpi.com
With growing concerns about COVID-19's hyperinflammatory condition and its potentially
damaging impact on the neurovascular system, there is a need to consider potential …

[HTML][HTML] Development of a targeted hydrophilic interaction liquid chromatography-tandem mass spectrometry based lipidomics platform applied to a coronavirus …

Z Zhang, M Singh, A Kindt, AB Wegrzyn… - … of Chromatography A, 2023 - Elsevier
The importance of lipids seen in studies of metabolism, cancer, the recent COVID-19
pandemic and other diseases has brought the field of lipidomics to the forefront of clinical …

GANE can improve lung fibrosis by reducing inflammation via promoting p38MAPK/TGF-β1/NF-κB signaling pathway downregulation

EA Mohamad, ZN Mohamed, MA Hussein… - ACS …, 2022 - ACS Publications
There is a trend to use nanoparticles as distinct treatments for cancer treatment because
they have overcome many of the limitations of traditional drug delivery systems. Gallic acid …

Vanin 1 gene role in modulation of iNOS/MCP-1/TGF-β1 signaling pathway in obese diabetic patients

YO Mosaad, MA Hussein, H Ateyya… - Journal of …, 2022 - Taylor & Francis
Introduction Cysteamine, a powerful endogenous antioxidant, is produced mostly by the
vanin-1 with pantetheinase activity. With regard to glycemic, inflammatory, and redox factors …

Optimization of Naringenin-loaded nanoparticles for targeting of Vanin-1, iNOS, and MCP-1 signaling pathway in HFD-induced obesity

A Salah, NM El-Laban, SM Alam, MS Islam… - International Journal of …, 2024 - Elsevier
Naringenin, a natural dihydrochalcone flavonoid, exhibits diverse pharmacological
properties. This study investigates the hypolipidemic effects of Nar-NPs on obese mice. The …

The effects of hospitalisation on the serum metabolome in COVID-19 patients

T Hensen, D Fässler, L O'Mahony, WC Albrich, B Barda… - Metabolites, 2023 - mdpi.com
COVID-19, a systemic multi-organ disease resulting from infection with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is known to result in a wide array of …

Salvia officinalis improves glycemia and suppresses pro-inflammatory features in obese rats with metabolic syndrome

DA Alsherif, MA Hussein… - Current Pharmaceutical …, 2024 - ingentaconnect.com
Objectives: Obesity is regarded as the main cause of metabolic diseases and a core factor
for all-cause mortality in the general population, notably from cardiovascular disease. The …

Structure activity relationship and molecular docking of some quinazolines bearing sulfamerazine moiety as new 3CLpro, cPLA2, sPLA2 inhibitors

MA Hussein, RM Borik, MS Nafie, HM Abo-Salem… - Molecules, 2023 - mdpi.com
The current work was conducted to synthesize several novel anti-inflammatory quinazolines
having sulfamerazine moieties as new 3CLpro, cPLA2, and sPLA2 inhibitors. The thioureido …

[HTML][HTML] Malva parviflora seed oil; Isolation, gas chromatographic profiling and its cardioprotective activity against myocardial infraction in animal model

MA Hussein, MS Islam, AA Ali, MS Mansour… - Journal of King Saud …, 2024 - Elsevier
Myocardial infarction (MI), one of the most perilous types of cardiac illness, carries a
significant burden of mortality and morbidity. This study aims to shed light on the impact of …