Synthetic biology applies genetic tools to engineer living cells and organisms analogous to
the programming of machines. In materials synthetic biology, engineering principles from …

Cells navigate environments, communicate and build complex patterns by initiating gene
expression in response to specific signals. Engineers seek to harness this capability to …

INTRODUCTION Cells respond to their environment, make decisions, build structures, and
coordinate tasks. Underlying these processes are computational operations performed by …

Synthetic biology aims to develop engineering-driven approaches to the programming of
cellular functions that could yield transformative technologies. Synthetic gene circuits that …

Efforts to construct synthetic networks in living cells have been hindered by the limited
number of regulatory components that provide wide dynamic range and low crosstalk. Here …

We often assume that the variables of functional and structural brain parameters—such as
synaptic weights, the firing rates of individual neurons, the synchronous discharge of neural …

Nucleic acids have attracted widespread attention due to the simplicity with which they can
be designed to form discrete structures and programmed to perform specific functions at the …

Synthetically engineered genetic circuits can perform a wide variety of tasks but are
generally less accurate than natural systems. Here we revisit the first synthetic genetic …

Global energy demand and environmental concerns have stimulated increasing efforts to
produce carbon-neutral fuels directly from renewable resources. Microbially derived …

As synthetic biology permeates society, the signal processing circuits in engineered living
systems must be customized to meet practical demands. Towards this mission, novel …