Amniotic membrane and its epithelial and mesenchymal stem cells as an appropriate source for skin tissue engineering and regenerative medicine

B Farhadihosseinabadi, M Farahani… - Artificial cells …, 2018 - Taylor & Francis
One of the main goals of tissue engineering and regenerative medicine is to develop skin
substitutes for treating deep dermal and full thickness wounds. In this regard, both scaffold …

Innovations in the treatment of dystrophic epidermolysis bullosa (DEB): current landscape and prospects

PC Hou, N Del Agua, SM Lwin, CK Hsu… - … and Clinical Risk …, 2023 - Taylor & Francis
Dystrophic epidermolysis bullosa (DEB) is one of the major types of EB, a rare hereditary
group of trauma-induced blistering skin disorders. DEB is caused by inherited pathogenic …

Investigational treatments for epidermolysis bullosa

PC Hou, HT Wang, S Abhee, WT Tu… - American Journal of …, 2021 - Springer
Epidermolysis bullosa (EB) is a heterogeneous group of rare inherited blistering skin
disorders characterized by skin fragility following minor trauma, usually present since birth …

Comparison of similar cells: Mesenchymal stromal cells and fibroblasts

B Ugurlu, E Karaoz - Acta histochemica, 2020 - Elsevier
Almost from all organs, both mesenchymal stromal cells and fibroblasts can be isolated.
Mesenchymal stromal cells (MSCs) are the most preferred cellular therapeutic agents with …

Mesenchymal stem cells' seeded amniotic membrane as a tissue-engineered dressing for wound healing

HR Aghayan, MS Hosseini, M Gholami… - Drug Delivery and …, 2022 - Springer
Different biomaterials have been used as biological dressing for wound regeneration. For
many decades, human amniotic membrane graft (AM) has been widely applied for treating …

Epidermolysis bullosa: a review of the tissue-engineered skin substitutes used to treat wounds

A du Rand, JMT Hunt, V Feisst… - Molecular Diagnosis & …, 2022 - Springer
Skin wound healing is a crucial process for regenerating healthy skin and avoiding the
undesired consequences associated with open skin wounds. For epidermolysis bullosa …

Challenges in treating genodermatoses: new therapies at the horizon

MA Morren, E Legius, F Giuliano… - Frontiers in …, 2022 - frontiersin.org
Genodermatoses are rare inherited skin diseases that frequently affect other organs. They
often have marked effects on wellbeing and may cause early death. Progress in molecular …

Current topics in Epidermolysis bullosa: Pathophysiology and therapeutic challenges

K Natsuga, S Shinkuma, CK Hsu, Y Fujita… - Journal of …, 2021 - Elsevier
Epidermolysis bullosa (EB) is a group of inherited skin and mucosal fragility disorders
resulting from mutations in genes encoding basement membrane zone (BMZ) components …

[HTML][HTML] Nanostructured fibrin-agarose hydrogels loaded with allogeneic fibroblasts as bio-dressings for acute treatment of massive burns

B Arribas-Arribas, B Fernández-Muñoz… - Biomedicine & …, 2023 - Elsevier
The prompt management of patients with massive burns is essential to maximize survival by
preventing infection, hemorrhage, fluid and heat loss, and to optimally prepare the wound …

Recent advances in the induced pluripotent stem cell‐based skin regeneration

S Choudhury, N Surendran… - Wound Repair and …, 2021 - Wiley Online Library
Skin regeneration has been a challenging clinical problem especially in cases of chronic
wounds such as diabetic foot ulcers, and epidermolysis bullosa‐related skin blisters …