Local anesthetics are the only class of drugs that can fully block nociceptive impulses from
reaching the cerebral cortex and, thus, they represent the only means of completely …

The use of multimodal anaesthesia and analgesia is desirable as part of a complete
analgesic plan. Analgesic strategies for perioperative pain treatment include combinations …

Local anesthetics reversibly block the generation and propagation of electrical impulses in
nerves, thereby causing sensory and motor blockade. They are primarily used for local and …

Traditionally, bioanalytical laboratories do not report actual concentrations for samples with
results below the LOQ (BLQ) in pharmacokinetic studies. BLQ values are outside the method …

Objectives To investigate the effect of 5% lidocaine patches on postoperative analgesia in
dogs undergoing hemilaminectomy. Materials and Methods Client‐owned dogs undergoing …

Local and regional anesthetic techniques are a vital component in the provision of balanced
anesthesia. There are many benefits to incorporating regional anesthesia into analgesic …

Purpose Poststernotomy pain (PSP), a primary concern after sternotomy, can negatively
affect patients' satisfaction with surgery and quality of life. Many clinical trials have been …

Objective To evaluate the transdermal local anaesthetic effect of lidocaine or lidocaine
combined with prilocaine or tetracaine in horses. Study design Experimental, randomized …

Opioids form an integral part of an anesthesia regime to provide perioperative analgesia,
sedation, and anesthetic‐sparing effects in small animals. Opioid alternative techniques are …

Objective To compare the analgesic effect of surgical wound infiltration with liposomal
bupivacaine (LB) to saline placebo in dogs after tibial plateau leveling osteotomy (TPLO) …