Despite the widespread use of the cell-surface receptor CD44 as a marker for antigen (Ag)-
experienced, effector and memory T cells, surprisingly little is known regarding its function …

Abstract Interleukin-7 (IL-7) is an essential cytokine for the development and homeostatic
maintenance of T and B lymphocytes. Binding of IL-7 to its cognate receptor, the IL-7 …

Pyridinyl imidazole inhibitors, particularly SB203580, have been widely used to elucidate
the roles of p38 mitogen-activated protein (MAP) kinase (p38/HOG/SAPKII) in a wide array of …

Abstract Interleukin-7 (IL-7) is an essential cytokine for T-cell development and homeostasis.
It is well established that IL-7 promotes the transcriptional down-regulation of IL7RA, leading …

The metabolic and cell cycle status of primary T lymphocytes conditions their susceptibility to
human immunodeficiency virus (HIV) and HIV-derived vectors. While in fully quiescent T …

The field of cytokine research is expanding at a rapid pace Contributions from the major
leading groups in the world on the structure and biological properties of cytokine and …

Interleukin 7 (IL-7), originally described as a B cell growth factor, has recently been found to
play a critical role in T and B lymphocyte development and function. This study evaluated the …

Glucocorticoids are agents endowed with powerful immunosuppressive and anti‐
inflammatory properties partially related to the inhibition of adhesion‐related processes. We …

The discovery of lymphokines stemmed from their ability to promote T-lymphocyte
proliferation in vitro. Even after 20 years of in tensive investigation, crucial aspects remain to …

The residues located at the carboxyl terminus of helix D in interleukin-7 (IL-7) have
previously been targeted as important for recruitment and binding to the γ chain component …