Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …

Peroxisomal fatty acid degradation in the yeast Saccharomyces cerevisiae requires an array
of β-oxidation enzyme activities as well as a set of auxiliary activities to provide the β …

Peroxisomes are organelles involved in many metabolic processes including lipid
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …

Lipid droplets (LDs) and peroxisomes are ubiquitous organelles with central roles in
eukaryotic cells. Although the mechanisms involved in biogenesis of these organelles …

Peroxisomes are rapidly degraded during amino acid and oxygen deprivation by a type of
selective autophagy called pexophagy. However, how damaged peroxisomes are detected …

Many proteins contain targeting signals within their sequences that specify their delivery to
particular organelles. The peroxisomal targeting signal-1 (PTS1) is a C-terminal tripeptide …

Lipid droplets (LDs) and peroxisomes are central players in cellular lipid homeostasis: some
of their main functions are to control the metabolic flux and availability of fatty acids (LDs and …

Peroxisomes are organelles that carry out β-oxidation of fatty acids and amino acids. Both
rare and prevalent diseases are caused by their dysfunction. Among disease-causing …

We describe a genome-wide characterization of mRNA transcript levels in yeast grown on
the fatty acid oleate, determined using Serial Analysis of Gene Expression (SAGE) …

PEX19 is a chaperone and import receptor for newly synthesized, class I peroxisomal
membrane proteins (PMPs). PEX19 binds these PMPs in the cytoplasm and delivers them to …