Antibody-mediated rejection of solid-organ allografts

A Loupy, C Lefaucheur - New England Journal of Medicine, 2018 - Mass Medical Soc
Antibody-Mediated Rejection of Solid-Organ Allografts This review focuses on current
standards for management of antibody-mediated rejection in solid-organ transplant …

The immunological basis of liver allograft rejection

V Ronca, G Wootton, C Milani, O Cain - Frontiers in immunology, 2020 - frontiersin.org
Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …

[HTML][HTML] 2016 comprehensive update of the Banff working group on liver allograft pathology: introduction of antibody-mediated rejection

AJ Demetris, C Bellamy, SG Hübscher, J O'leary… - American Journal of …, 2016 - Elsevier
The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature
evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France …

Clinical recommendations for posttransplant assessment of anti–HLA (Human Leukocyte Antigen) donor-specific antibodies: A Sensitization in Transplantation …

C Lefaucheur, K Louis, AB Morris, JL Taupin… - American Journal of …, 2023 - Elsevier
Abstract Although anti–HLA (Human Leukocyte Antigen) donor-specific antibodies (DSAs)
are commonly measured in clinical practice and their relationship with transplant outcome is …

[HTML][HTML] From immunosuppression to tolerance

DH Adams, A Sanchez-Fueyo, D Samuel - Journal of hepatology, 2015 - Elsevier
The past three decades have seen liver transplantation becoming a major therapeutic
approach in the management of end-stage liver diseases. This is due to the dramatic …

Antibody-mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies

NM Valenzuela, EF Reed - The Journal of clinical …, 2017 - Am Soc Clin Investig
Solid organ transplantation is a curative therapy for hundreds of thousands of patients with
end-stage organ failure. However, long-term outcomes have not improved, and nearly half of …

Antibody-mediated rejection of the liver allograft: An update and a clinico-pathological perspective

BT Lee, MI Fiel, TD Schiano - Journal of hepatology, 2021 - Elsevier
Antibody-mediated rejection after liver transplantation is an under-recognised cause of
allograft injury. While definitions of acute and chronic antibody-mediated rejection have …

The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection

KA Thomas, NM Valenzuela, EF Reed - Trends in molecular medicine, 2015 - cell.com
The pathophysiology of antibody-mediated rejection (AMR) in solid organ transplants is
multifaceted and predominantly caused by antibodies directed against polymorphic donor …

[HTML][HTML] Proposed diagnostic criteria for chronic antibody-mediated rejection in liver allografts

JG O'Leary, J Cai, R Freeman, N Banuelos… - American Journal of …, 2016 - Elsevier
Donor-specific alloantibodies (DSA) can cause acute antibody-mediated rejection (AMR) in
all solid organ allografts. However, long-term outcome in patients with posttransplant DSA …

An update on liver transplantation: a critical review

J Neuberger - Journal of autoimmunity, 2016 - Elsevier
Liver transplantation, although now a routine procedure, with defined indications and
usually excellent outcomes, still has challenges. Donor shortage remains a key issue …