Purpose To describe clinical features, therapeutic approaches, and prognostic factors in
pediatric patients with atypical teratoid/rhabdoid tumors (ATRT) treated at St Jude Children's …

The hSNF5 subunit of human SWI/SNF ATP-dependent chromatin remodeling complexes is
a tumor suppressor that is inactivated in malignant rhabdoid tumors (MRTs). Here, we report …

There is a growing appreciation of the role that epigenetic alterations can play in
oncogenesis. However, given the large number of genetic anomalies present in most …

Abstract hSNF5, the smallest member of the SWI/SNF chromatin remodeling complex, is lost
in most malignant rhabdoid tumors (MRT). In MRT cell lines, reexpression of hSNF5 induces …

Background p53 mutations are relatively uncommon in medulloblastoma, but abnormalities
in this cell cycle pathway have been associated with anaplasia and worse clinical outcomes …

Atypical teratoid/rhabdoid tumor (AT/RT) is a rare tumor of the CNS mostly seen in infants
and is often associated with a dismal outcome. Despite the heterogeneous morphology …

Chapter 7 deals with neuroblastoma (NB) and related tumors. The specific genetic events
responsible for NB development have not been established, even though several changes …

✓ An atypical teratoid/rhabdoid tumor of the central nervous system (CNS) is a rare,
aggressive neoplasm found in infants and children that has similar characteristics to CNS …

We report two infant cases with atypical teratoid/rhabdoid tumor (AT/RT) located in the
cerebellar vermis and spinal cord. MRI showed the tumors were isointense on T 1-weighted …

This paper presents the case of an eight-year-old girl who presented with headache and
vomiting and was found to harbor a right fronto-temporo-parietal, partially cystic and …